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Biomedical subjects

G S Mazurkevich

Publications and source records attributed to G S Mazurkevich.

At least 19 recordsLinked to original sources
PubMed1987

[Regulatory and executive mechanisms of adaptation to hypovolemia].

In anesthetized cats, suppression of reflexes from the main zones of cardiac vascular system induced with hypovolemia, was accompanied by raising the total peripheral resistance of vessels and the systemic arterial pressure. Some cats had a redistribution of cardiac output similar to changes of regional blood flow occurring in the defense response: the enhancement of the cardiac output directed towards the hind-limbs along with limitation of oxygen consumption in this region.

Acid-Base Equilibrium↗
PubMed1976

[Adrenal cortical function in rats with traumatic shock following removal and deafferentation of the hypothalamus].

The 11-oxycorticosteroid (11-OCS) content was studied in the blood plasma of sham-operated rats, rats with intact, ablated and deafferentated medial-basal hypothalamus (MBH) in traumatic shock. There were no reliable differences in the 11-OCS basal level in various groups of rats. MBH ablation led to the reduction in the weight of adrenal and pituitary glands and MBH deafferentation -- to increase in the weight of the former. The 11-OCS level was reliably higher in traumatic shock of rats with complete MBH deafferentation than in sham-operated animals.

11-Hydroxycorticosteroids↗
PubMedDate not supplied

[One of the possible means of restoring the circulating blood volume in shock].

The possibility of increasing the efficacy of restoration of the circulating blood volume (CBV) in shock was demonstrated in experiments on 33 anesthesized female cats. Intramuscular injection of lactin one hour before blood loss (2% of body mass) in a dose of 5 U/kg or its intravenous infusion 90 minutes after blood loss in a dose of 50 U/kg was attended by restoration of the plasma volume in 5 hours. The prospects of further research into improvement of the efficacy of CBV in shock through activation of the body's reserves are substantiated.

Animals↗