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Biomedical subjects

G S Radugina

Publications and source records attributed to G S Radugina.

At least 19 recordsLinked to original sources

[The possibility for the intravital diagnosis of a dissecting aortic aneurysm].

On the basis of experience gained in vital diagnosis of dissecting aneurysm, its thoracic portion, in 3 patients the authors note that accurate diagnosis of this pathology cannot be made without analysis of a complex of diagnostic studies that rely on a correct assessment of clinical manifestations of the disease. The following items should be noted: particular features of the pain syndrome, migration of the pain zone and relapsing character of pain; lack of a clear-cut interrelation between intensity and duration of pain and frequency of development of cardiogenic shock and cardial asthma; correlation between changes in blood count (leukocytosis) and blood levels of transaminases; absence of the typical ECG features of myocardial infarction, and character of time-related changes.

Aortic Dissection↗

[The health status of workers engaged in the manufacture of inorganic manganese salts].

Workers engaged in the production of inorganic manganese salts revealed lesions of the upper respiratory pathways (catarrhal and subatrophic rhinitis, pharyngitis, laryngitis), skin (contact and allergic dermatitis), cardiovascular disorders. They also showed changes of renal function,mineral metabolism,acid stability of erythrocytes. Activation of the B-system of immunity and allergization of the body are also observed.

Adult↗

[Working conditions and health status of workers engaged in the production of zinc compounds].

It was established that industrial shops engaged in zinc compounds' processing were characterized by considerable temperature shifts, relative humidity and air motion changes. In drying and packing shops, concentrations of the final product dusts were established at 0.8-2 mg/m3. The major occupational pathology was constituted by skin and upper respiratory tract diseases, including allergic and contact dermatitis, chronic pharyngitis, tonsillitis and rhinitis. Blood tests revealed B-lymphocytes: increases, circulating immune complexes and considerable levels of lymphocytic spontaneous blastotransformations. Erythrocytic acidic hemolysis was markedly changed, which proved disbalances in the system of red blood.

Acetates↗

[Difficulties in the diagnosis of primary cancer of the liver].

Case records have been analyzed for 92 patients with primary cancer of the liver. The discrepancies between the clinical and postmortem diagnosis reached 31%. It appeared that the exact diagnosis depended on valid evaluation of the disease history, clinical signs and findings at special examinations rather than on the number of investigations. Associated liver cirrhosis recorded in 24% of cases put another obstacle for a precise vital diagnosis. The study has furnished evidence for a judgment on the incidence of hepatic cancer, concomitant cirrhosis, possible etiologic factors, the state of clinical diagnosis and causes of death.

Aged↗

[Levamisole and splenin in combined therapy of patients with bronchiectasis].

Follow-up of 114 patients with bronchiectasis has demonstrated that immunomodulation agents levamisole and splenin included in combined treatment augment their therapeutic effect and normalize the immune status of patients. This is manifested by normalization of the amount and functional activity to T-lymphocytes, the content of IgG, IgM and IgA and the autoimmune shifts. A favourable effect was encountered significantly more often than that in patient who were treated by the traditional methods without the use of the immunomodulation agents and in those who were given only levamisole and splenin together with anti-bacterial and hygienic therapy.

Adjuvants, Immunologic↗

[Differential diagnosis in fever of unknown origin].

A study of 156 patients admitted to the clinic with the diagnosis of "fever of unclear genesis" indicates that the most frequent cause of this condition are pathological processes in the abdominal and retroperitoneal space, renal diseases, patients with bacterial endocarditis and connective tissue diseases. Detailed clinical analysis makes it possible mostly to establish a correct diagnosis at early terms of the disease.

Abdomen↗

[Correction of hepatic morphofunctional disorders in mechanical jaundice of a nontumorous nature].

The authors examined 68 patients with cholelithiasis complicated by mechanical jaundice. The clinical course of the disease, functional and morphological changes of the liver were elucidated. Different hepatic functions were involved: the protein-forming, pigmentary, enzymatic, etc. Morphological changes of the liver revealed severe dystrophic changes in the liver parenchyma including necrosis of some parts the liver. The employed complex of therapeutic measures allowed to carry out operative interventions in more favourable conditions that reduced the number of postoperative complications.

Biopsy↗

[Training and practical summer work of 4th-year medical students].

Practical work of the 4th-year medical students is aimed at strengthening the knowledge acquired by them at medical and theoretical chairs, further extension and improvement of practical skills, acquaintance with the organization of curative work, physicians' labour conditions at the regional and country level, principles of public health organization and antiepidemic activity.

Clinical Clerkship↗

[The treatment of peptic ulcer].

Problems are discussed on the differential pathogenetic treatment of patients with duodenal ulcer. Variants are singled out of the course of ulcer disease depending on the prevalence of clinical symptoms. The characteristic features of these symptoms are described and the most rational and individualized therapeutic complexes for each of these clinical variants are evaluated.

Antacids↗