PubMed Health⌕ Search

Biomedical subjects

G S Stepanov

Publications and source records attributed to G S Stepanov.

At least 19 recordsLinked to original sources
PubMed1991

[Feto-placental system in diabetes mellitus and hydramnios].

The fetoplacental system of 132 women with diabetes mellitus and 85 healthy women was studied during the third pregnancy trimester. Blood estradiol and urinary estriol levels were found-reduced in the diabetics, particularly in those with insulin-dependent diabetes. Blood progesterone and oxytocinase levels were found unchanged. These parameters lowered in diabetic glomerulosclerosis. If pregnant diabetics develop hydramnion, their blood estradiol, progesterone, prolactin, and oxytocinase levels increased.

Adult↗
PubMed1982

[The hypothalamo-hypophyseo-ovarian systems in rats after deafferentiation of the mediobasal hypothalamus].

Complete surgical deafferentation of the medio-basal hypothalamus (MBH) in rats entails suppression of the oestrus cycle as well as a decrease of luteinizing hormone, estrogens and progesterone release into the blood due to a sharp fall of the luliberine content in the median eminence and arquate nuclei. No connection was revealed between the character of oestrus disturbances and the extent of damage or isolation of the arquate, ventromedial, supraoptic and paraventricular nuclei and the amount of Homori-positive neurosecreted in the MBH. In development of permanent diestrus the MBH isolation was more complete than in the preservation of irregular cycle. The luliberine seems to be produced mainly in the anterior hypothalamus of rats whereas the MBH alone fails to maintain even its tonic secretion. Even in complete surgical isolation of the MBH, separate fibers of the luliberinergic cells penetrate into the MBH maintaining there a certain amount of luliberin and preserving synthesis of the luteinizing hormone in the hypophysis with its decreased release into the blood.

5-Hydroxytryptophan↗
PubMed1976

[Hormonal function of the ovaries in women with breast hyperplasia].

In females showing fibrous-cystic mastopathy and fibroadenomatosis of mammary glands a specific form of progesterone insufficiency- relative one, was revealed, a high persistantly maintained level of urine pregnandiol and blood progesterone in a luteal phase (indicating a high hormonal activity of the corpus luteum) being observed. But luteal transformations were insignificant both in endometrium and vaginal epithelium, a moderate hypoestrogenemia being noted in the first phase and increased estrogen excretion- in the second phase of the cycle.

Adult↗