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Biomedical subjects

G Scadding

Publications and source records attributed to G Scadding.

24 records · Page 2Linked to original sources
PubMed1989

Intestinal permeability to 51Cr-labelled ethylenediaminetetraacetate in food-intolerant subjects.

Intestinal permeation of 51Cr-labelled ethylenediaminetetraacetate (51Cr-EDTA) was normal in 8 food-intolerant patients. Following ingestion of the offending food stuff there was a significant (p less than 0.003) decrease in the permeation of 51Cr-EDTA but the same phenomenon was observed in control subjects (n = 5) following cereal. Eight patients were tested following ingestion of lentil puree and subsequently with lentil puree containing the food to which they were sensitive. In these patients there was a significant increase in the permeation of 51Cr-EDTA following the 2nd test (p less than 0.01), but this was of insufficient magnitude to be of diagnostic use. These results show that food intolerance does involve some, but not gross changes in intestinal permeability to 51Cr-EDTA.

Adult↗
PubMed1986

Bronchospasm following the use of vecuronium.

A case history is presented which records bronchospasm due to vecuronium. Immunological investigations, including basophil degranulation tests, indicated that the bronchospasm was not caused by direct histamine release and was not IgE mediated. It was of interest that intradermal testing gave a positive wheal response against neuromuscular agents other than those involved in the anaesthetic procedure under investigation. A positive reaction to vecuronium was only obtained when given in a high concentration and accords with the general belief that vecuronium has extremely low potential for histamine release.

Aged↗
PubMed1977

Primary amenorrhoea: the ambiguous non-entity.

Hypothalamic-pituitary activity was investigated in 20 women with primary amenorrhoea, in whom gonadal dysgenesis and lower Müllerian duct anomalies had been excluded. There was no specific or uniform pattern of response to luteinising hormone-releasing hormone and no evidence of a common defect at pituitary-hypothalamic level to account for the absence of spontaneous menstruation. Six women had hyperprolactinaemia; of these five had radiological evidence of pituitary enlargement. The conventional distinction between "primary" and "secondary" amenorrhoea should be abandoned, and, in common with current practice for other endocrine glands, primary amenorrhoea should indicate an abnormality of the gonad itself and secondary amenorrhoea an abnormality that results from hypothalamic-pituitary dysfunction.

Adolescent↗