PubMed Health⌕ Search

Biomedical subjects

G Scalise

Publications and source records attributed to G Scalise.

At least 181 records · Page 10Linked to original sources
PubMedDate not supplied

Turbidimetric and visual criteria for in vitro susceptibility testing of Cryptococcus neoformans clinical isolates.

The drug concentration which inhibited 50% of growth (IC50), the lowest drug concentration at which growth was less than 30% of that in a positive control well (IC30), the visual minimal inhibitory concentration (MIC visual), were applied to study the effects of fluconazole, itraconazole, amphotericin B and flucytosine against 27 isolates of Cryptococcus neoformans by a broth microdilution technique. When the recommendations established by NCCLS Subcommittee on Antifungal Susceptibility Test were applied for the visual reading of the microplates, the results were comparable with those obtained by the turbidimetric method. No statistically significant differences between MIC visual and IC30 readings were observed with the azoles. There were, however, differences with amphotericin B and flucytosine. In absolute terms MICs of amphotericin B and flucytosine showed higher values than IC30s and IC50s.

AIDS-Related Opportunistic Infections↗
PubMedDate not supplied

Tinea capitis due to Microsporum gypseum in an adult.

A case of tinea capitis due to Microsporum gypseum in an adult is described. An otherwise healthy 69-year-old woman presented two large patches of slightly erythematous scaling alopecia localized on the vertex and on the left parietal region of the scalp. The only subjective sign was itching. A mycological culture was positive for Microsporum gypseum. Tinea capitis is uncommon in adults; furthermore, isolation of Microsporum gypseum from this type of lesion is rare.

Age Factors↗
PubMedDate not supplied

[Incidence of Australia antigen (HBs Ag) in a group of apparently healthy population of the Sassari province].

In 3828 subjects (1489 males and 2339 females) apparently healthy was investigated the presence in the serum of Australia antigen and of corrispondent antibody with electrosyneresis, the activity of the G6PD eritrocytic and the eventual condition of carrier of microcytemic tare. An incidence of HBs Ag of 1.83% (2.75% in males and 1.24% in females) without any statistically important differences in the age groups and habitual residence and also the grade of G6PD eritrocytary activity was detected. A more elevated statistical incidence was observed among the carriers of thalassemic caracter never transfused. The anti HBs Ag antibodes were observed in 0.26% of the examined subjects.

Antibodies, Viral↗
PubMedDate not supplied

Therapy with immunoglobulin of the HIV infection related idiopathic thrombocytopenia.

The Authors report that in their experience in the therapy of HIV infection related thrombocytopenia with IG at the classic dose of 0.4 gr/Kg/day x 5 days. Moreover they report their experience in a patient with repeated single-dose infusions at low dosage. They treated four patients, who were drug-addicts, with HIV infection thrombocytopenia that didn't exceed 50,000/mm3. Anti-platelets antibodies tested with an indirect method weren't found in any of the patients examined. Among those patients three were of Group III CDC and one of Group IV C1 CDC. Among the first group the best results were obtained in two patients with the immunocompromission of average seriousness but one of these had a rapid decrease in platelets count. In the others where results were low a severe immunocompromission was apparent and probably a severe damaged Reticulo Endothelial System (RES) function. So the AA think that function of RES may be important in the forecast of clinical response. The Authors conclude moreover that good results were obtained with a single-dose infusion at low dosage even if they observed a progressive decrease of response. They propose such a therapy if there isn't an emergency after tested RES function.

Adult↗
PubMedDate not supplied

[Concentrations of the IgM and antibodies for the TORCH complex in the umbilical blood (author's transl)].

The Authors have found both IgM and antibodies for the TORCH complex in the umbilical blood of 1500 newborns. In 119 (7.9%) there was an increase of IgM. In 23% of these newborns there were present antibodies for rubella, in 21% antibodies for toxoplasma, in 15.9% antibodies for cytomegalovirus, and in 19.2% antibodies for herpes simplex. However there was no statistical correlation between the antibodies for the TORCH complex and the increase of IgM.

Antibodies↗
PubMedDate not supplied

[Thymic hormone treatment of acute and chronic respiratory infections in the elderly].

Respiratory infections are particularly frequent in aged subjects and cause severe and often inauspicious complications) such as compromised cell-mediated immunity. Preliminary data suggest thymopentin treatment in a population of elderly subjects affected by relapses of bronchial disease. The effects of the therapy are adequately monitored controlling immunologic parameters.

Acute Disease↗
PubMedDate not supplied

[Infections of Salmonella in Sassari (Sardinia, Italy). Epidemiology from 1973 to 1976 (author's transl)].

The epidemiology of Salmonella infections in Sassari in the last four years was reported. The remarkable increase of gastroenteritis caused by uncommon Salmonella and by S. wien in 1975 and 1976 was point out: about all cases were related with 3 epidemic episodes in hospitalized patients that were notified as paratyphoid cases in 91% and as infancy's gastroenteritis in 9%. The 201 strains of Salmonella isolated from June 1975 to May 1976 belong for 91% to group B (for 80,5% to S. wien), for 2% to group C1, for 1,5% to group C2, for 5% to group D1 and for 0,5% to group E4. The hypothesis on introduction of S. wien in Sardinia were examined; the rules for limitation of Salmonella diffusion and for prevention of the endemicity of new imported strains, were examined.

Adult↗