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Biomedical subjects

G Scansetti

Publications and source records attributed to G Scansetti.

At least 37 records · Page 2Linked to original sources

[The risk of oligomers in the textile industry].

An experimental research was carried out at the Institute of Occupational Health of Turin University on the risks following exposure to oligomers with particular reference to the textile industry. A group of 36 Sprague-Dawley rats were injected endotracheally with a suspension of dust collected from various sections of twisting and spinning departments while 6 rats used a referent groups, were treated with normal solution in the way. Five rats had pneumonia and 1 rat showed the presence of aspecific granuloma whereas the histological patterns for the other rats were found to be similar to those of the control group. In the Authors' opinion it is impossible at the moment, to give a definite conclusion as to the role of oligomers in lung damage.

Animals↗

Pleural plaques and lung asbestos bodies in the general population: an autoptical and clinical-radiological survey.

Of 218 necropsies of male subjects, pleural hyaline plaques were detected in 67 (30%). The prevalence of pleural plaques was found to be related to age at death and to history of previous occupational contact with asbestos. The presence of asbestos bodies in lungs was also associated with pleural plaques; however, the reliability of the presence of ferruginous bodies as an indicator of exposure to asbestos is questioned. The role of environmental exposure will be better demonstrated at the end of an investigation on place of residence, which is still in progress. Chest X-rays showed little sensitivity for use in epidemiological surveys.

Age Factors↗

Mortality of chrysotile asbestos workers at the Balangero Mine, Northern Italy.

The mortality from 1946 to 1975 of over 900 North Italian chrysotile asbestos workers first employed between 1930 and 1965 has been studied. Nine deaths were certified as attributable to asbestosis, and eleven to lung cancer. One death was attributed to mesothelioma of pleura but this diagnosis was not supported by histological examination. Comparison with the national figures for all Italy did not reveal an excess of deaths from lung cancer but during the last quinquennium of observation, the SMR for lung cancer rose to 206. Simulation experiments enabled a dust index in fibre/years to be attached to each man in the cohort. All but two of the deaths from lung cancer occurred in the higher exposure group. The relative risk of lung cancer in this group was 2.89. The eleven workers who died from lung cancer were all cigarette smokers. A further period of observation is required to monitor the mortality of the surviving workers.

Asbestos↗

[Control of occupational exposure to benzene in a chemical plant].

Later on detection of several cases of acute myelotoxic intoxications the use of benzene as a solvent has been banned in Italy since 1963 (Law n. 245). Its consumption has therefore been confined to synthesys processes in petrolchemical industry. The hazards arising from the operations performed in an open air chemical plant which produces alkylbenzene were monitored by the AA. The synthesis occurs in a closed system which provides opportunities for benzene exposure during filling, control and maintenance operations. Nine environmental samples out of 10 showed benzene concentrations above 10 ppm with peaks up to 110 ppm. Long term air sampling showed values ranging from 12 to 75 ppm. Urinary phenol elimination has been measured showing values above 50 mg/1 for approximately 20% of workmen. The difficulties pertaining to an adequate control of benzene exposure in chemical plants are discussed. Being skin contact a mode of entry of apreciable concern, the AA. stress out that priority in exposure monitoring should be given to biological tests such as urinary phenol level and benzene concentration in expired air measurements.

Air Pollutants↗

Cement, asbestos, and cement-asbestos pneumoconioses.

The incidence and characteristics of cement-asbestos pneumoconiosis were compared with those of asbestosis and cement pneumoconiosis in three homogeneous samples of cases. The clinical, functional, and radiological features of cement-asbestos pneumoconiosis are similar to those of classical asbestosis, but the observed changes are less common and occur after a longer exposure.

Asbestosis↗

[Arterial hypertension and work activities].

Human work may be a causative agent in arterial hypertension (A.H.), for example through the action of toxic or physical agents such as lead and noise. The working environment is also a useful place for A.H. screening and assessment of therapeutic compliance. However, new cases of A.H. should be treated and followed up in order to avoid increased absenteeism. The choice of therapeutic drugs should take account of the type of job (i.e., amount of energy expenditure, sensorial charge, hot environment) and the shift, so as to achieve a single daily administration (for example using combined drugs). Hypertensive subjects could be advised against night work.

Absenteeism↗