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Biomedical subjects

G Sengupta

Publications and source records attributed to G Sengupta.

9 recordsLinked to original sources
PubMed2000

Review of trends of malaria in an urban community of Calcutta during 1984-1997.

The trends in the malaria situation over the last 14 years in an urban community of Calcutta with a population of 1,04,000 have been analysed with particular reference to the malaria epidemic which took place in Calcutta in November-December, 1995. Annual and monthwise data on malariometric indices pertaining to 1984-1997 were collected from health centre records. The total number of blood slides examined every year has steadily increased from around 8,000 in 1984 to more than 23,000 in 1996 with some decline in 1997. About 95% of the confirmed malaria cases were of the benign tertian type, while remaining 5% were of the malignant tertian type. The slide vivax rate has steadily declined over the years 1984-1997 from around 50 per cent in 1984 to between 20 to 30 per cent during 1993-1997. The slide falciparum rate over the same period varied between 0.5 to 2 per cent and did not show any clear secular trend. The annual parasite incidence (API) which varied cyclically between 40 to 60 per thousand during 1984-87 increased (with a cyclical trend superimposed on a secular increasing trend) to vary between 50 to 70 per thousand during 1994-97. The 1995 winter epidemic of malaria was characterised by an increased occurrence of both P vivax and P falcipanrum malaria.

Disease Outbreaks↗
PubMed1986

Immunodiagnosis of filariasis.

The sensitivity and specificity of the enzyme-linked immunosorbent assay (ELISA), the indirect haemagglutination (IHA) test and the counter-current immuno-electrophoresis test (CIEP) were assessed in the diagnosis of filariasis. Positive reactions were observed in 91% and 86% of cases by ELISA and IHA respectively. CIEP detected only 31.5% of cases. Cross-reaction due to intestinal nematodes was observed in 80% of cases by both ELISA and IHA whereas with CIEP cross-reaction was observed in 10% of cases. The microfilaria count was inversely proportional to the antibody titre among asymptomatic carriers. ELISA was the most sensitive test, followed by IHA and then CIEP. CIEP, though it detected only a small number of cases, was observed to be the most specific.

Antigens, Helminth↗
PubMedDate not supplied

A controlled study on haemograms of malaria patients in Calcutta.

A study was carried out at the Urban Health Centre, Chetla, Calcutta to evaluate the efficacy of quantitative buffy coat (QBC) analysis of haemograms in malaria patients suffering from fever with bodyache and chill and/or rigour attending the Fever Treatment Depot during a three months period (March-June 1996) who had undergone both malaria parasite study and haematological investigation by the QBC method from blood samples collected by finger prick. To avoid bias, malaria parasite studies and haemograms were done separately, and investigators were kept 'blind' about the results of other investigations. The haematological findings obtained of 180 slide-positive malaria cases were compared with a sample of 177 age- and sex-matched slide-negative controls selected by random sampling. The results revealed that haemoglobin levels (g%), haematocrit values (%), WBC and platelet counts of malaria cases were significantly lower than in the matched controls. Thus, QBC estimation correlates well with existing knowledge about malarial haematology. This relatively easier, quicker and reliable method of taking haemograms may be recommended for field testing for assessing haematological parameters of malaria cases under field conditions, before its introduction for large-scale use.

Adolescent↗
PubMedDate not supplied

Prevalence of the type of hepatitis virus in hospitalized jaundiced individuals.

The prevalence of different types of hepatitis virus was estimated in 185 hospitalized jaundiced patients. It was found that 41.08% were positive for HBs Ag by ELISA method. The jaundiced group was also tested for IgM antibody and for total antibodies (IgG and IgM) to HAV infection by ELISA method and 5.40% were found to be positive. All patients in the jaundiced group had serum bilirubin above normal values. It was, therefore, assumed that the rest 52.92% were suffering from Non A Non B virus infection.

Adolescent↗
PubMedDate not supplied

Aortoarteritis involving supra-aortic trunks: a profile of six cases.

Six patients (2 male, 4 female; age range 24 to 36 years) with aortoarteritis involving the supra-aortic trunks were investigated and surgically managed by bypass graft with either preclotted dacron or polytetrafluoroethylene (PTFE) in an urban institute. There has been no mortality and post-operative functional recovery has been satisfactory in all the cases.

Adult↗