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Biomedical subjects

G Shindo

Publications and source records attributed to G Shindo.

At least 37 records · Page 2Linked to original sources
PubMed1985

Total cavopulmonary shunt with replacement of common atrioventricular valve for an infant with single atrium and single ventricle.

A 22-month-old male infant with single atrium, single ventricle, regurgitant common atrioventricular valve, pulmonary atresia, patent ductus arteriosus, and inferior vena cava defect with azygos connection was treated successfully with total cavopulmonary shunt and replacement of the common atrioventricular valve. The indications for total cavopulmonary shunt in the management of univentricular heart with azygos continuity are discussed.

Abnormalities, Multiple↗
PubMed1983

[Open heart surgery for removal of secondary cardiac tumors].

Recent remarkable development of the non-invasive diagnostic apparatus such as two dimensional echocardiography, computed tomography and RI angiography improves early diagnosis for secondary cardiac tumors and promotes surgical treatments for them. Five cases of secondary intracardiac tumors underwent open heart surgery using cardiopulmonary bypass with successful removal. Although a case of direct invasion of a malignant thymoma into the pericardium, RA and SVC was lost at ICU after surgery because of massive hemorrhage followed by LOS, another 4 cases, i.e., a 27 year-old female with implantation of LA myxoma into the RA and RV, a case with intracavitary extension of leiomyosarcoma of the IVC, a case of intravenous extension of the uterine leiomyomatosis through the IVC to the pulmonary artery and a case of intravenous extension of chondrosarcoma of the left fibula to the heart are alive actively. Open heart surgery has become acceptable treatment for cases with secondary intracavitary cardiac tumors in order to rescue emergency cases with circulatory obstruction by the tumor mass, to make sure a pathological diagnosis of unknown origin and to promote further chemotherapy and/or radiation therapy after surgery. Our surgical results may support these active treatments for secondary cardiac tumors.

Adult↗
PubMed1982

Left ventricular morphometric estimation of the coarctation complex in the first year of life.

Coarctation complex is a serious congenital cardiovascular malformation in infants. It is associated with severe congestive cardiac overload and high mortality even after surgical treatment. To investigate left ventricular performance, quantitative morphometry and histometry of the left ventricle were carried out in 19 autopsied patients who died without surgical intervention. The following results were obtained: 1. Coarctation of the aorta was found to selectively affect the left ventricle, showing a volume overload response without effectively adapting to the pressure overload; the right ventricle showed a significant reaction to the pressure overload. 2. The coronary arterioles responded to the pressure load in the left ventricle. In order to promptly recover left ventricular function, simple coarctectomy without VSD closure or other procedures is advisable for treatment of the coarctation complex in the early months of life.

Aortic Coarctation↗
PubMed1981

Repair of major intracardiac anomalies associated with atrioventricular discordance.

Thirty-five patients with atrioventricular (AV) discordance underwent repair of major intracardiac defects. Ventricular septal defect (VSD) was the most frequently encountered lesion, present alone or in combination with other lesions in 86% of these patients. Pulmonary stenosis (51%) and tricuspid insufficiency (37%) were the other lesions encountered. The initial operative mortality of 8.6% is approaching that for these same defects when repaired in the patient with normal atrioventricular connections. However, the late mortality of 19% with an average follow-up of 4.4 years is higher than expected in the absence of AV discordance. Reoperation for residual or recurrent defects was required in 9 of the 32 survivors and was associated with a mortality of 33%. Seven of the 9 reoperations were required for tricuspid valve dysfunction. Elective repair of major anomalies in association with AV discordance can be accomplished safely, but these patients require careful long-term follow-up in anticipation of late problems.

Adolescent↗
PubMed1980

Results of repair of coarctation of the aorta during infancy.

One hundred ninety-one infants under 1 year of age underwent repair of coarctation of the aortz during a recent 14 year period. All operations were performed on an urgent, nonelective basis. One third of the infants had isolated coarctation (Group I), one third had associated ventricular septal defect (VSD) (Group II), and one third had other complex anomalies (Group III). The operative mortality rate has decreased to 4% in infants with isolated coarctation of the aorta but remains at 25% for repair of coarctation in association with significant intracardiac disease (Groups II and III). The late mortality rate also was affected by intracardiac defects. No late deaths occurred in Group I patients, whereas the 5 year mortality rate was 25% in Groups II and III. Surgical repair was by resection and end-to-end anastomosis in most (92%) cases. Recurrent coarctation, as defined by arm/leg blood pressure gradient at rest, developed in 54% of the survivors within 7 years following operation. Recoarctation did not affect late mortality rate. Twelve children (11.1% of survivors) underwent repair of recoarctation during this interval. Hypertension developed in 27% of the children followed more than 5 years after repair and was always associated with residual arm/leg blood pressure gradient. There are no cases of idiopathic hypertension in this series.

Aorta, Thoracic↗