Biomedical subjects

G Sieben

Publications and source records attributed to G Sieben.

23 records · Page 2Linked to original sources

PubMed1980

Pathogenesis of Binswanger chronic progressive subcortical encephalopathy.

We studied the clinicopathologic findings in four hypertensive patients with multiple leukomalacia, demyelinated lesions, and lacunar state. Only one patient had clinical evidence of dementia. The periventricular watershed infarcts were attributed to transient episodes of cardiac failure in brains with a compromised circulation in the territory of the deep perforating branches. These observations suggest that Binswanger encephalopathy does not differ from multi-infarct dementia.

Aged↗

PubMedDate not supplied

Early ultrastructural changes in aging rat gastrocnemius muscle: a stereologic study.

Normal gastrocnemius muscle of Wistar rats at various ages to 2 1/2 years was studied. No light microscopic or qualitative electron microscopic changes were seen. However, stereologic determinations revealed significant reductions in volume and surface densities of sarcoplasmic reticulum, t-tubular system, and glycogen content. These alterations were considered to be the morphologic expression of the very early age-related changes in gastrocnemius muscle.

Aging↗

PubMedDate not supplied

Radicular lesions in tuberculous meningitis. A clinicopathological study.

In the present work, the involvement of cranial and spinal nerve roots in tuberculous meningitis was studied. Cranial nerves of 11 cases and the spinal roots of three patients were examined by means of serial sections of the base of the brain, brainstem and spinal cord. Although entrapment of the nerves by the tenacious inflammatory exudate was prominent, vasculitis lesions of the cranial nerves and spinal roots were also frequently observed. The latter could be an additional cause of nerve palsies in tuberculous meningitis.

Adult↗

PubMedDate not supplied

The syndrome of the anterior inferior cerebellar artery. A clinicopathologic study of two cases.

The clinicopathologic findings in two cases of infarct in the territory of the anterior inferior cerebellar artery are presented. A distinction is made between a minimal and a maximal syndrome. In the first case the infarct in the basis pontis correlated well with the existence of a pure motor hemiplegia. In the second case more extensive pontine infarction gave rise to a more classical brainstem syndrome. In 52 anatomical specimens the origin, course and angioarchitecture of the anterior inferior cerebellar artery were studied, showing the variability in supply area. Only the paramedial and intermediolateral territories were found to be mostly constant.

Aged↗

PubMedDate not supplied

Thrombosis of the mesencephalic artery. A clinico-pathological study of two cases and its correlation with the arterial vascularisation.

Two cases of thrombosis of the mesencephalic artery are described : the location of the occlusion and of the infarcted area in the upper mesencephalon is correlated to the clinical syndrome, in particular to the existence or the absence of an oculomotor paralysis. In addition 27 normal brains are examined by means of the translucidation and the radiographic techniques after filling of the arterial system with a colloidal barium sulphate solution. This study supports the subdivision of the upper mesencephalon into five vascular territories and justifies the denomination of mesencephalic artery, which supplies a transitional region between the diencephalon and the brainstem.

Aged↗