Biomedical subjects
G Signorelli
Publications and source records attributed to G Signorelli.
Raman scattering from fractals: Simulation on large structures by the method of moments.
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Collective dynamics in water by high energy resolution inelastic X-ray scattering.
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Brillouin and Raman cross sections in silicate glasses.
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Synthesis and preliminary pharmacological evaluation of pidotimod, its enantiomer, diastereomers and carboxamido derivatives.
A new compound with a peptide-like structure, (R)-3-[(S)-(5-oxo-2-pyrrolidinyl)carbonyl]-thiazolidine-4-carboxylic acid, its enantiomer, diastereomers and carboxamido derivatives were synthesized and tested for immunostimulant activity. Synthesis, preliminary, pharmacological data and structure-activity relationships are reported. (R)-3-[(S)-(5-Oxo-2-pyrrolidinyl)carbonyl]-thiazolidine-4-carboxylic acid (Ib, Pidotimod, PGT/1A, CAS 121808-62-6) was selected for further research.
[A histological and ultrastructural study of the effects of the argon laser scalpel on the kidney].
The authors carried an histological and ultrastructural study on rat kidney following polar excision by argon laser. The involvement of the remainder portion of the kidney was evaluated analysing the depth of the damage induced by the laser radiation. Restitution ad integrum was found below 360 micron thickness with a different involvement of the various kidney components. Glomeruli showed a deep damage caused by intravascular photocoagulation. On the contrary, tubular and extracellular damage was less serious and the damaged area extended for only 240 micron from the section, probably for a lack of absorbance of the argon radiation by clear and water-rich tissues.
Elasto-optic constants in silicate glasses: Experiment and theory.
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Microscopic model for the two-phonon Raman spectra of alkali halides.
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Vibrational dynamics and Raman scattering in fractals: A numerical study.
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Disorder-induced light scattering in solids: Microscopic theory and applications to some model systems.
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Absolute two-phonon Raman cross section in potassium chloride.
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Numerical study of Raman scattering from fractals.
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[Synthesis of gallic acid derivatives with L-thiazolidin-4-carboxylic acid and study on their antiradical and antitoxic activity].
The authors report the synthesis of three new derivatives of gallic acid with L-thiazolidine-4-carboxylic acid. The new compounds were tested for radical scavenger activity against doxorubicin toxicity in mice and for antitoxic activity against acetaldehyde and formaldehyde toxicities in rats. Unlike the utilized standards, the new compounds show no activity.
[3-substituted 1,2-benzisoxazole and their neuroleptic activity].
The authors report the synthesis of two new derivatives of 3-substituted 1,2-benzisoxazole. The new molecules (P-1368, P-1370), evaluated in many pharmacological C.N.S. tests, show interesting neuroleptic activity but inferior to those of haloperidol and chlorpromazine.
Raman activity in the beta phase of silver iodide: Low-temperature ordered crystal.
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[Use of argon laser in experimental liver surgery].
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[Beta blockers and the climateric syndrome].
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[Correlations of cardiodynamic parameters and the adrenergic system in essential arterial hypertension at rest and during exertion].
The study of hemodynamic and humoral changes stressed the possibility--statistically significant for the values of end diastolic volume (EDV), ejection fraction (EF), end systolic volume (ESV), dopamine (DA), norepinephrine (NE)-to point out the differences between normotensive and hypertensive subjects in the pre-clinic stage during exercise test, and to predict their evolution along with the relative diagnostic, therapeutic and prognostic corollaries.