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G Sinkovics

Publications and source records attributed to G Sinkovics.

8 recordsLinked to original sources

Rabbit dysentery: 1. Clinical, epizootological and bacteriological studies.

Individual and epizootological observations on scouring in a large flock of three-to 10-week-old growing rabbits indicate that spread from animal to animal is not characteristic in outbreaks of rabbit dysentery. Although the disease occurs chiefly after weaning, precipitation of the symptoms seems to be unrelated to weaning stress. Intestinal flora studies on infected and control animals have shown that the bacteriological background of the condition is varied. Marked increase of coliforms over controls occurred in 70 per cent of the cases, coliforms and clostridia had both increased in 20 per cent, and clostridia only in 5 per cent. In the remaining 5 per cent the intestinal flora did not differ from normal, although death from rabbit dysentery was readily obvious. Microscopic examinations for coccidial oocysts of mucosal scrapings from different intestinal segments have shown that oocyst counts sufficient to give rise to clinical coccidiosis were only exceptionally present.

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Rabbit dysentery: 2. Therapeutic experiments.

Control of rabbit dysentery in three-to 10-week-old growing-broiler rabbits was attempted by individual therapy of diseased animals and prophylactic flock treatment. Antibiotics selected on the basis of previous resistance tests failed on both therapeutic and preventive application, but a notable reduction of losses could be achieved by prophylactic medication with coccidiostatics. Clinically ill animals did not, however, respond to coccidiostatic therapy. Analysis of intestinal bacterium flora in the diseased animals and the good results of preventive coccidiostatic treatment suggests that the basic mechanism underlying rabbit dysentery is coccidial infection.

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Rabbit dysentery: 3. Diagnostic differentiation.

The diagnostic differentiation of rabbit mucoid enteritis from rabbit dysentery by age and post mortem findings is described. The condition termed as "rabbit dysentery" affects three- to 10-week-old growing rabbits and is essentially an acute coccidiosis, while "mucoid enteritis" develops in older rabbits as a sequel to constipation for six to eight days. The main differentiating feature of the two conditions, which have often been confused with one another owing to similarity of symptoms, is the characteristics dissimilarity of gross changes in the caecum.

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Intestinal flora studies in rabbit mucoid enteritis.

The clinical and bacteriological examination of spontaneous and experimental cases of mucoid enteritis on a large rabbit farm indicated that the mucin accumulations in the colon are a consequence of constipation. This opinion is supported by the results obtained following ligation of the proximal colon. These findings suggest that rabbit mucoid enteritis is not a specific disease entity but a general response to the factors which cause constipation. Studies of the bacterial flora of the gut in spontaneous and experimental cases suggest that while there is a notable increase in the number of coliforms and clostridia over the healthy controls, these organisms only play a secondary role.

Animals↗