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Biomedical subjects

G Sjøgaard

Publications and source records attributed to G Sjøgaard.

At least 37 records · Page 2Linked to original sources
PubMed2000

Consistency of motor-unit identification during force-varying static contractions.

Due to inter-operator variability, two operators were used to assess the consistency of motor unit (MU) identification during ramp contractions, by the comparison of semi-automatic decompositions of the same recordings. Static shoulder abduction was performed against a force transducer in a position with the upper arms vertical and elbows flexed to 90 degrees. The subjects followed an 8-s force trajectory: 30% maximum voluntary contraction (MVC, 2 s), a reduction in force from 30% to 0% MVC (2 s), 0% MVC (1 s), an increase in force from 0 to 30% MVC (2 s), and 30% MVC (1 s). Muscle activity was recorded from the supraspinatus muscle with a quadripolar needle. From six recordings of 8 s duration, a total of 2527 MU firings were identified by both operators, and 93% of these were identified identically into 31 MUs. Both operators identified 8 of these MUs as continuously firing, 5 as only being active either before or after the 1 s at 0% MVC, and 18 as being de-recruited during force decreases and recruited during force increases. Both operators agreed that 16 of these 18 MUs were de-recruited at a higher force level than that at which they were recruited, which may be due to the electromechanical delay. The coefficient of variation for double determination of the results obtained by operators A and B was 8.5% for the number of MU firings, 4.5% for the MU mean firing rate, and 8.4% for the MU action potential (MUAP) amplitude. Therefore, the operator interactive decomposition method was considered to be valid for studying recruitment and de-recruitment as well as firing rate and MUAP amplitude during static, force-varying ramp contractions.

Adult↗
PubMed2000

Kinetics and energetics during uphill and downhill carrying of different weights.

During physically heavy work tasks the musculoskeletal tissues are exposed to both mechanical and metabolic loading. The aim of the present study was to test a biomechanical model for prediction of whole-body energy turnover from kinematic and anthropometric data during load carrying. Total loads of 0, 10 and 20 kg were carried symmetrically or asymmetrically in the hands, while walking on a treadmill (4.5 km h(-1)) horizontally, uphill, or downhill the slopes being 8%. Mean values for the directly measured oxygen uptake ranged for all trials from 0.5 to 2.1 l O2 min(-1), and analysis of variance showed significant differences regarding slope, load carried, and symmetry. The calculated values of oxygen uptake based on the biomechanical model correlated significantly with the directly measured values, fitting to the line Y = 0.990 X + 0.144, where Y is the estimated and X is the measured oxygen uptake in l min(-1). The close relationship between energy turnover rate measured directly and estimated based on a biomechanical model justifies the assessment of the metabolic load from kinematic data.

Adult↗
PubMed2000

Aspects of shoulder function in relation to exposure demands and fatigue - a mini review.

OBJECTIVE: To discuss the literature on control and function of multiple muscle systems with special focus on shoulder and upper extremity under submaximal conditions. DESIGN: The paper is a mini review based on 31 studies. BACKGROUND: Control mechanisms underlying the recruitment and gradation of muscle activity in complex multiple muscle systems during various voluntary exertions is still not fully understood. Load sharing principles may be influenced by several factors like work demand, fatigability, metabolic factors etc. METHODS: Several methods, e.g., electromyography, intramuscular pressure, and tissue oxygenation are used. The definition of fatigue is discussed. RESULTS AND CONCLUSION: A relatively fixed load sharing of the shoulder muscles has been found at low load levels, submaximal speeds and with a limited range of movements of the arms for healthy subjects. However, the load sharing of the shoulder muscles can be changed to some extent in response to fatigue, mental demands, visual feedback and in patients suffering from disorders in the upper extremities. It is hypothesized that lack of ability to redistribute muscle activation pattern in the shoulder region or the upper extremity increases the risk of development of work related symptoms.

Biomechanical Phenomena↗
PubMed2000

Muscle involvement during intermittent contraction patterns with different target force feedback modes.

OBJECTIVE: Assess the effect of different feedback modes during intermittent contractions on primary and assessory muscle activity. BACKGROUND: Intermittent contractions and physiological responses have been studied in laboratory settings. However, the feedback given to the subjects regarding timing and force level is generally not specified. DESIGN: Repeated measure design in which six subjects in randomized order performed two experimental conditions only differing in feedback mode. METHODS: Intermittent static elbow flexion was performed against either a fixed-force transducer (visual feedback) or a weight to be held in position (proprioceptive feedback) both corresponding to 30% maximal voluntary contraction. Contraction and relaxation timing of 6 and 4 s, respectively, was shown on a VDU screen as colour code identical in both conditions. RESULTS: Test contractions performed before and following 30 min of intermittent contractions showed larger fatigue development with proprioceptive feedback than visual feedback. Also rating of perceived exertion increased more during proprioceptive feedback than visual feedback. This may in part be explained by small differences in the mechanics during the two different feedback modes. In line with this, EMG recorded from four shoulder/arm muscles analyzed for amplitude and frequency showed similar activity initially; but later, during the 30 min contraction larger amplitudes were attained during proprioceptive feedback than visual feedback. CONCLUSIONS: Feedback mode significantly effects the muscle involvement and fatigue during intermittent contractions. RelevanceIntermittent contractions are common in many work places and various feedback modes are being given regarding work requirements. The choice of feedback may significantly affect the muscle load and consequently the development muscle fatigue and disorders.

Biomechanical Phenomena↗
PubMed2000

Impaired sarcoplasmic reticulum Ca(2+) release rate after fatiguing stimulation in rat skeletal muscle.

The purpose of the study was to characterize the sarcoplasmic reticulum (SR) function and contractile properties before and during recovery from fatigue in the rat extensor digitorum longus muscle. Fatiguing contractions (60 Hz, 150 ms/s for 4 min) induced a reduction of the SR Ca(2+) release rate to 66% that persisted for 1 h, followed by a gradual recovery to 87% of prefatigue release rate at 3 h recovery. Tetanic force and rate of force development (+dF/dt) and relaxation (-dF/dt) were depressed by approximately 80% after stimulation. Recovery occurred in two phases: an initial phase, in which during the first 0.5-1 h the metabolic state recovered to resting levels, and a slow phase from 1-3 h characterized by a rather slow recovery of the mechanical properties. The recovery of SR Ca(2+) release rate was closely correlated to +dF/dt during the slow phase of recovery (r(2) = 0.51; P < 0.05). Despite a slowing of the relaxation rate, we did not find any significant alterations in the SR Ca(2+) uptake function. These data demonstrate that the Ca(2+) release mechanism of SR is sensitive to repetitive in vitro muscle contraction. Moreover, the results indicate that +dF/dt to some extent depends on the rate of Ca(2+) release during the slow phase of recovery.

Animals↗
PubMed2000

Dynamics and consequences of potassium shifts in skeletal muscle and heart during exercise.

Since it became clear that K(+) shifts with exercise are extensive and can cause more than a doubling of the extracellular [K(+)] ([K(+)](s)) as reviewed here, it has been suggested that these shifts may cause fatigue through the effect on muscle excitability and action potentials (AP). The cause of the K(+) shifts is a transient or long-lasting mismatch between outward repolarizing K(+) currents and K(+) influx carried by the Na(+)-K(+) pump. Several factors modify the effect of raised [K(+)](s) during exercise on membrane potential (E(m)) and force production. 1) Membrane conductance to K(+) is variable and controlled by various K(+) channels. Low relative K(+) conductance will reduce the contribution of [K(+)](s) to the E(m). In addition, high Cl(-) conductance may stabilize the E(m) during brief periods of large K(+) shifts. 2) The Na(+)-K(+) pump contributes with a hyperpolarizing current. 3) Cell swelling accompanies muscle contractions especially in fast-twitch muscle, although little in the heart. This will contribute considerably to the lowering of intracellular [K(+)] ([K(+)](c)) and will attenuate the exercise-induced rise of intracellular [Na(+)] ([Na(+)](c)). 4) The rise of [Na(+)](c) is sufficient to activate the Na(+)-K(+) pump to completely compensate increased K(+) release in the heart, yet not in skeletal muscle. In skeletal muscle there is strong evidence for control of pump activity not only through hormones, but through a hitherto unidentified mechanism. 5) Ionic shifts within the skeletal muscle t tubules and in the heart in extracellular clefts may markedly affect excitation-contraction coupling. 6) Age and state of training together with nutritional state modify muscle K(+) content and the abundance of Na(+)-K(+) pumps. We conclude that despite modifying factors coming into play during muscle activity, the K(+) shifts with high-intensity exercise may contribute substantially to fatigue in skeletal muscle, whereas in the heart, except during ischemia, the K(+) balance is controlled much more effectively.

Acid-Base Equilibrium↗
PubMed1999

Muscle responses to simulated torque reactions of hand-held power tools.

The aim of this work was to investigate physiological responses to torque reaction forces produced by hand-held power tools used to tighten threaded fasteners. Such tools are used repetitively by workers in many industries and are often associated with upper limb musculoskeletal complaints. The tools considered for stimulation in this study had straight handles and required from 100 to 400 ms to tighten fasteners to a peak torque of 1.0 to 2.5 Nm and from 50 to 150 ms for the torque to decay to zero. A tool stimulator was constructed to apply a programmed torque profile to a handle similar to that of a straight in-line power screwdriver. Wrist flexor and extensor surface EMGs and handle position were recorded as subjects held handles subjected to controlled torque loads that tended to flex the wrist. It was found that: (1) very high EMG values occurred even though torques were of short duration (50 to 600 ms) and the peak torques were low (7-28% of maximum strength); (2) high EMGs in anticipation of torque are directly related to torque build-up rate and peak torque; (3) high peak flexor and extensor EMGs during and following torque onset are related to torque build-up rate and peak torque; (4) minimum time of peak EMGs of 72-87 ms following the onset of torques with 50 ms build-up suggests the contribution of an extensor muscle stretch reflex component; delayed peak for longer build-ups suggests a central control of muscle force in response to torque; (5) angular excursions of handles increase with decreasing torque build-up time and increasing torque magnitude causes increasing eccentric work; (6) the results show that the slow torque build-up times (450 ms) correspond to minimum peak EMGs; and (7) accumulated EMGs increase with increasing torque and torque build-up times. Further studies are needed to evaluate fatigue and musculoskeletal injuries associated with prolonged periods of tool use.

Adult↗
PubMed1998

Motor unit activation patterns during concentric wrist flexion in humans with different muscle fibre composition.

Muscle activity was recorded from the flexor carpi radialis muscle during static and dynamic-concentric wrist flexion in six subjects, who had exhibited large differences in histochemically identified muscle fibre composition. Motor unit recruitment patterns were identified by sampling 310 motor units and counting firing rates in pulses per second (pps). During concentric wrist flexion at 30% of maximal exercise intensity the mean firing rate was 27 (SD 13) pps. This was around twice the value of 12 (SD 5) pps recorded during sustained static contraction at 30% of maximal voluntary contraction, despite a larger absolute force level during the static contraction. A similar pattern of higher firing rates during dynamic exercise was seen when concentric wrist flexion at 60% of maximal exercise intensity [30 (SD 14) pps] was compared with sustained static contraction at 60% of maximal voluntary contraction [19 (SD 8) pps]. The increase in dynamic exercise intensity was accomplished by recruitment of additional motor units rather than by increasing the firing rate as during static contractions. No difference in mean firing rates was found among subjects with different muscle fibre composition, who had previously exhibited marked differences in metabolic response during corresponding dynamic contractions. It was concluded that during submaximal dynamic contractions motor unit firing rate cannot be deduced from observations during static contractions and that muscle fibre composition may play a minor role.

Adult↗
PubMed1998

Effect of speed and precision demands on human shoulder muscle electromyography during a repetitive task.

Effects of speed and precision on electromyography (EMG) in human shoulder muscles were studied during a hand movement task where five points were marked repeatedly with a pencil. Six female subjects performed with three precision demands and at four speeds. Three of the speeds were predefined, while the last speed was performed as fast as possible. The EMG were recorded from 13 shoulder muscles or parts of muscles. Elbow velocity, acceleration and rectified EMG were calculated for each task. The mean elbow velocity and acceleration increased with speed and precision demands. There was an increase in EMG as the speed demand increased for all three precision demands (P < 0.001), and as the precision demand increased for the two highest predefined speed demands (P < 0.05). The combination of a high speed and a high precision demand resulted in the highest EMG. Different EMG levels were attained for the 13 muscles and the supraspinatus muscle always showed the highest normalized EMG. However, analysis of variance showed the same relative increase for all muscles with speed and precision demands. The EMG changes in response to precision demand can only be explained in part by the differences in movement velocity and acceleration, and other factors such as increased co-contraction must also be taken into account.

Aged↗
PubMed1998

A model predicting individual shoulder muscle forces based on relationship between electromyographic and 3D external forces in static position.

To study the potentiality for developing an EMG-based model for the human shoulder, mapping of relations between static hand forces and electromyographic (EMG) activity of 13 shoulder muscles, were performed. The procedure was to perform by the hands slowly varying isometric forces up to 20% maximum voluntary force in the three-dimensional space. By combining these data with literature values on muscle physiological cross-sectional area and moment arm data, an EMG-based model was developed for estimating muscle forces in the glenohumeral joint. The model was validated for one standardized position by comparing joint moment, calculated from EMG by using the model, with moments from the external force. The highest correlation between these moments was found assuming a linear EMG/force calibration at low force level (< 20% MVC), giving correlations from 0.65 to 0.95 for the abduction/adduction moment and from 0.70 to 0.93 for the flexion/extension moment, for the six subjects. Moments calculated from EMG were for most subjects somewhat lower than the moments from the external force; the mean residual error ranged from 1.6 to 9.9 Nm. Taking this into account, the results can be used for assessment of muscle forces based on recordings of external forces at the hands during submaximal static work tasks without substantially elevated arms.

Adult↗
PubMed1998

Muscle injury in repetitive motion disorders.

Documentation of causality between repetitive motions and musculoskeletal disorders calls for detailed understanding of the exposure variables and the corresponding physiologic responses in the biologic tissues. Quantification of the kinetics in some jobs characterized by repetitive motions is summarized with the physiologic responses in the muscles. Muscle activity pattern was studied in different shoulder muscles or muscle parts, and in elbow and wrist flexor muscles. Activity pattern was dependent on the kinetics of the work requirements. This holds true for the compound electromyographic signal and for single motor units. Low threshold motor units have been identified that are recruited continuously, the so called Cinderella fibers. The physiologic consequences of prolonged muscle fiber activity are reviewed, revealing mechanisms for the development of necrotic changes in the muscle, which support the likelihood of work relatedness for musculoskeletal disorders.

Cumulative Trauma Disorders↗
PubMed1996

Potassium and fatigue: the pros and cons.

A general finding is that muscle activity leads to potassium fluxes across the muscle membrane as well as to muscle fatigue, defined as a reduction in the force-generating capacity of the muscle. However, much controversy exists regarding the causal role of potassium in fatigue development. The experimental model used is decisive in this context, e.g. whether we study intact in vivo organs in situ with voluntary contractions and reflex feedback for cardiorespiratory regulation, or whether we study in vitro isolated muscles or cells-or even skinned fibres. In the latter models, clear evidence has been presented that Ca2+ is the variable significant for force development and that K+ may be ignored. However, in the in situ situation the limiting link in the chain leading to muscle contraction may be one preventing the Ca2+ release from taking place. The sites are the triads, T-tubules, and the surface membrane. The function of the latter two regarding action potential amplitude and propagation depends on [K+] gradients. Again, conflicting results exist regarding the electrophysiological changes and [K+] in fatigue. The activity pattern must then be taken into consideration. During high-intensity (high-frequency) activity the increased interstitial [K+] has been demonstrated to relate to fatigue, while in low-intensity fatiguing protocols, the T-tubule may be the limiting site. This fits with the concept of interstitial [K+] playing an essential role as a regulatory feedback mechanism, e.g. adjusting muscle blood flow to the metabolic load during muscle activity.

Animals↗
PubMed1996

Musculoskeletal Disorders: Work-related Risk Factors and Prevention.

Work-related musculoskeletal disorders cause chronic pain and functional impairment, impose heavy costs on society, and reduce productivity. In this position paper from the Scientific Committee for Musculoskeletal Disorders of the ICOH, the most important risk factors at work are described. Work-related musculoskeletal disorders have high incidences and prevalences among workers who are exposed to manual handling, repetitive and static work, vibrations, and poor psychological and social conditions. The application of ergonomic principles in the workplace is the best method for prevention. International organizations should develop standards, common classifications, and terminologies. Surveillance systems should be further developed nationally and in workplaces, and more effort should be directed to information dissemination, education, and training.

Journal Article↗
PubMed1996

Motor control and kinetics during low level concentric and eccentric contractions in man.

Motor unit (MU) recruitment patterns were studied in 6 female subjects during dynamic contractions at relative workloads corresponding to 10% maximum voluntary contraction. The contractions consisted of a 20 degree elbow flexion (concentric contraction) and extension (eccentric contraction) and MU action potential trains were recorded from the brachial biceps muscle. The mean angular velocity of the dynamic contractions was 10 degrees/s, during which a total of 119 MUs were identified. Additionally, a few contractions were studied at 20 degrees/s during which 30 MUs were identified, and 9 MUs during the 40 degrees/s contraction. About 60% of the identified MUs were active during the concentric as well as the eccentric phase for each of the velocities. Mean firing rate decreased significantly when the contraction changed from concentric to eccentric, whereas the number and properties of identified active MUs were similar. This emphasizes firing rate modulation as important during low level dynamic contractions rather than selective recruitment of different types of MUs in the concentric versus the eccentric phase. Similar kinetic demands occur frequently in occupational tasks, especially during monotonous work. The present data indicate that only a limited pool of MUs are being recruited during such tasks. Extensive recruitment of these MUs may cause fatigue and start a potentially vicious circle leading to work-related muscle disorders.

Action Potentials↗
PubMed1995

Role of interstitial potassium.

Interstitial potassium concentration, [K+], is modulated during muscle activity due to a number of different mechanisms: diffusion and active transport of K+ in combination with water fluxes. The relative significance of the various mechanisms for muscle function is quantified. The effect of interstitial [K+] locally on the single muscle fiber is discussed along with its effect on the cardiovascular and respiratory systems and its role in motor control. It is concluded that K+ may play a significant role in the prevention as well as the development of fatigue.

Animals↗