Primary hydatid cyst of the gallbladder.
An unusual case of hydatid cyst of the gallbladder is presented. The difficulties in diagnosis are discussed. There is no other report of such a cyst in the world literature.
Aged↗
Biomedical subjects
G Skalkeas
Publications and source records attributed to G Skalkeas.
Surgical management of diseases of the adolescent female breast: a clinicopathologic study.
Sixty-three patients, ages 10 to 20 years with diseases of the breast were operated on during a 10 year period. A variety of pathologic entities were found. The most common were diagnoses fibroadenoma, cystic disease, and cellulitis with abscess formation. Malignancy was found in three patients: lobular carcinoma in situ in one, angiosarcoma in the second, and lymphosarcoma in the third.
Abscess↗
Toluidine blue O used to identify intricate bleeding points and minute ulcerations of the stomach during surgery. An experimental study in dogs.
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Animals↗
Esophageal atresia with tracheoesophageal fistula.
Our experience in treating ten full-term and six premature infants with esophageal atresia and distal tracheoesophageal fistula was reported. Fourteen cases were treated by a one-stage procedure and two cases by a two-stage procedure. One patient died due to pulmonary infection following the one-stage procedure and one died of septicemia after the two-stage procedure. Anastomotic stricture developed in four cases and was treated successfully by dilatation.
Esophageal Atresia↗
Beneficial effect of omental wrapping of unsafe intestinal anastomoses. An experimental study in dogs.
The effect of omental wrapping on the safety of intestinal anastomosis was studied experimentally in 12 dogs. In six animals serving as controls, complete division of the small intestine and immediate restoration of continuity was carried out, after rendering the intestinal segment ischemic by ligating the mesenteric vessels for a distance of 10 cm. In a second group of animals, the ischemic anastomosis was wrapped with a pedicled strip of omentum. Gangrene and peritonitis developed in all animals of the control group, whereas the omental graft afforded complete protection against leakage from the devascularized anastomosis and peritonitis in the test animals.
Animals↗
Hepatography.
A method of hepatography in dogs is described in which contrast medium is infused via the external jugular and superior and inferior venae cavae and hepatic veins. Hepatograms taken by infusing different contrast media in the normal liver and in the liver subjected to parenchymatous damage are also analyzed in detail.
Animals↗
Anaesthetic management of reconstruction of the lower portion of the trachea. Case report.
A case of tracheal stenosis following chest injuries is reported. The anaesthetic technique used for partial resection of the intrathoracic portion of the trachea is described. Problems of ventilation during this type of operation are discussed.
Adult↗
Functioning metastatic parathyroid carcinoma.
A case of 53-year-old woman with a parathyroid adenoma and a parathyroid carcinoma with functioning metastases to the lungs, mediastinum and pleura is reported. The administration of inorganic phosphate solution failed to control hypercalcemia. The therapeutic methods available to deal with metastases are discussed.
Adenocarcinoma↗
[Aseptic urethritis in the post-pericardiotomy syndrome].
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Adult↗
Prognosis of mammary carcinoma in young women.
One hundred and sixty-two women with carcinoma of the breast, age 40 years or younger, were treated from 1950 to 1969. Mammary cancer is not uncommon in this age group. The 5 year survival rate among our operable patients was about 50 percent. The 5 year survival rate among patients 20 to 35 years of age was slightly higher than that in patients 36 to 40 years old. In stage B and more advanced breast cancer in young women, the outlook was poorer than in women 41 years and older. When axillary involvement is present during gestation or in the immediate postpartum period, the prognosis is especially poor. Young women have an unusually high proportion (35 percent) of low-grade, infrequently metastasizing tumors, such as medullary, intraductal, papillary, and lobular carcinomas. The presence of cancer in the axillary nodes at operation is the most important factor affecting prognosis in mammary cancer. From this study we can see no reason to consider carcinoma of the breast in young women a more lethal disease than that seen in their older counterparts.
Adenocarcinoma, Mucinous↗
Pharmacokinetics of arteether in dog.
A pharmacokinetic study has been conducted in six beagle dogs after i.m. administration of 25 mg/kg of arteether, a qinghaosu (artemisinin) derivative of high anti-malarial activity. Arteether plasma concentrations were measured during a 24 h period using HPLC with an electrochemical detector in the reductive mode. The pharmacokinetic parameters were established using an open two-compartment model. Results showed a relatively rapid absorption phase: T1/2ka was 0.300 +/- 0.096 h and a mean elimination half-life of 27.95 +/- 11.93 h. Cmax was 110 +/- 16 ng/ml, Cltot/F was 1.69 +/- 0.34 ml/min and AUC was 2797 +/- 476 ng/ml/h.
Animals↗
Mechanism of growth retardation following chronic administration of beta-adrenoceptor antagonists to developing rats.
A total of 112 3-week old Wistar rats were separated into eight groups: control groups I-IV (n = 62) and propranolol-treated groups V-VIII (n = 50). Propranolol hydrochloride (100 mg/kg) was present in the rats' drinking water until 26 weeks of age and growth rates of all groups were monitored daily until 53 days of age and thereafter every third day throughout the study. Chronic oral propranolol administration produced growth retardation (P less than 0.05) in both sexes that was reversible when treatment was discontinued. Organ weights were generally smaller in propranolol-treated rats; on the other hand, the ratio of most organ weights per 100 g of body weight was greater in propranolol-treated rats (especially females). The radio-immunological determination of plasma growth hormone showed increased concentrations of growth hormone in propranolol-treated rats (P less than 0.05), whereas hypothalamic somatostatin content was not significantly changed. The results showed that the retarded growth rate following chronic oral propranolol administration to growing rats was independent of changes in plasma growth hormone and hypothalamic somatostatin concentrations, and that retardation was entirely reversible when the beta-adrenoceptor antagonist was discontinued.
Adrenergic beta-Antagonists↗
Thyroid disease in children and adolescents.
Thyroid diseases in children and adolescents are not common. The present paper describes 73 patients, aged 5 to 18 years, who had thyroid disease which was treated by surgery. Of these, 18 had diffuse simple goiter, 11 had diffuse toxic goiter and 44 had nodular goiter. Of those patients with nodular goiter, 34 had adenomatous goiter, one had lymphocytic thyroiditis, one had lymphosarcoma and eight had cancer. In the patients with nodular goiter under the age of ten years, 40% had cancer, and of those aged 11 to 18 years, 14.7% had cancer. Thyroid nodules were more frequent in girls than in boys, but the incidence of cancer in nodular goiter was higher in boys than in girls.
Adolescent↗