Biomedical subjects
Publications and source records attributed to G Soferman.
A case of nonfatal Flavobacterium CDC group IIb bacteremia in a hospitalized woman is presented. The portal of entry of the organism was either an intravenous line or an open, eroded wound associated with bilateral breast carcinoma. Flavobacterium infections in the post-neonatal age group are reviewed.
Based on the vasodilator properties of calcium antagonists, verapamil was recently introduced into the treatment of arterial hypertension. The present study was undertaken to examine the long-term efficacy of this drug in mild and moderate hypertension. In 82 patients with uncontrolled primary or renal hypertension, verapamil was used either alone or in combination with other drugs. In six cases verapamil was withdrawn because of side effects. In the remaining patients a normal average blood pressure was achieved within 7.8 +/- 1.2 weeks of treatment with doses not exceeding 400 mg/day. This effect was maintained for up to 4 years of treatment, although tolerance seemed to develop in about 10% of the patients. In view of this good response and minimal side effects, it is concluded that verapamil is an effective addition to the antihypertensive arsenal.
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Extreme sinus bradycardia and T wave changes are described in a patient receiving lithium therapy. Ischemic heart disease was excluded by the results of radionuclide study and an exercise stress test. The electrocardiographic changes were shown to be related to lithium therapy, as documented by the inverse correlation between heart rate and plasma lithium levels.
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Explore the source record for details and available documents.
Explore the source record for details and available documents.