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Biomedical subjects

G Solarino

Publications and source records attributed to G Solarino.

17 recordsLinked to original sources
PubMed2001

A combined XPS-SEM/EDX investigation on explanted UHMW polyethylene acetabular cups: possible role of silicon traces in the wear debris.

An investigation was started aimed at a better understanding of the complex phenomena leading to chemical degradation and morphological deterioration of UHMW polyethylene cups in total hip prostheses. Analysis was performed on retrieved implants which needed revision due to inflammation and pain problems. Preliminary results obtained by parallel XPS and SEM/EDX experiments gave evidence, for the first time, that silicon traces are involved in the process of particle formation and segregation onto the surface of the cups. The extent of modification of the surface chemical composition of cups and the process of particle segregation seem to be correlated to both the implant time and to some particular features of patient (age, activity, style of life, etc.). Investigation on a large number of samples is in progress in order to test this hypothesis. The results obtained so far confirmed the potential of surface spectroscopies (XPS) in biomaterial investigations.

Journal Article↗
PubMed1996

Ageing is associated in females with a decline in the content and activity on the b-c1 complex in skeletal muscle mitochondria.

The activity of cytochrome-c oxidase [E.C. 1.9.3.1] and b-c1 complex [E.C. 1.10.2.2] and the content of cytochromes b, c + c1 and a + a3 in human skeletal muscle mitochondria from orthopaedic patients (108 women and 68 males), of age ranging between 10 and 50 years, have been analyzed. The activity of cytochrome c-oxidase declines with age both in females and males. The activity of b-c1 complex, which in young females is significantly higher than in young males, declines sharply in females, but not in males, with ageing. These results reveal that the content of active b-c1 complex in muscle mitochondria is specifically controlled by female sex hormones.

Adolescent↗
PubMed1996

Radiographic variables in normal and osteoarthritic hips.

The width of the weight-bearing surface (WBS) of the acetabulum and its obliquity; height, width, opening angle and alpha angle of the gothic arch; diameter of femoral head; the angle between the center of the femoral head and the most lateral point of the acetabulum (CE angle); neck-shaft angle (CCD angle); offset; angle of aperture, surface area, and volume of the spherical sector; radius and height of the spherical bowl; and distance from teardrop were assessed to study mechanically normal and frankly osteoarthritis hips. There appears to be a direct correlation between primary alterations of the above variables and development of osteoarthritis of the hip.

Aged↗
PubMed1995

Anterior cruciate ligament reconstruction. A comparison of 2 techniques.

This work compares the results of 2 different techniques of anterior cruciate reconstruction performed by 2 surgeons with the same rehabilitation program and same criteria of results evaluation. Forty-five patients were operated on using semitendinous tendon autograft, (average followup, 8 years 4 months), and 30 patients using bone patellar tendon bone autograft (average followup, 7 years 5 months). Functional results were evaluated using the Lysholm and Tegner rating systems, and clinical laxity or stability were evaluated using the Lachmann and Jerk tests. Articular stability and function were significantly better in the patients operated on using bone patellar tendon bone autograft.

Adolescent↗
PubMed1994

Decline with age of the respiratory chain activity in human skeletal muscle.

Mitochondrial respiratory systems have been screened in 63 orthopaedic patients of age ranging between 17 and 91 years. The results show a statistically significant definite decrease with ageing of mitochondrial respiratory activity with pyruvate plus malate, succinate and ascorbate plus TMPD. This pattern is associated with an equally significant decrease with age of the enzymatic activity of complex I, II and IV. No significant decrease with age is, on the contrary, observed in the mitochondrial content of cytochromes a+a3, and c+c1. Preliminary Western blot analysis indicates an altered polypeptide pattern in cytochrome c oxidase. This study provides evidence for a decline with age of mitochondrial respiratory activity in human skeletal muscle, affecting complex I, II and IV.

Adolescent↗
PubMed1990

Models of hip prosthesis mobilisation.

The mechanisms of prosthetic hip mobilisation are analysed, both in regard to the acetabular component and the femoral component. These are correlated with the clinical and radiographic manifestations with the aim of facilitating the comprehension and memorisation of different types of mobilisation. These are summarised in a chart illustrating the eight different mechanisms which provide both the orthopaedist and the radiologist with a rapid "aide memoire" when faced with a radiograph in a case of aseptic prosthetic hip mobilisation.

Acetabulum↗
PubMedDate not supplied

The surgical treatment of hallux valgus using distal metatarsal osteotomy and stabilization with a hallux splint. Preliminary results.

The preliminary results of the surgical treatment of hallux valgus using subcapitate chevron-type osteotomy of the 1st metatarsal modified using a dynamic interfragmentary device are reported. The method satisfies the need to restore angular metatarsophalangeal and intermetatarsal values and improves metatarsal pain caused by hallux valgus correction, which influences the cosmetic results.

Adolescent↗
PubMedDate not supplied

Multiple osteoid osteoma. A clinical case.

Osteoid osteoma is a benign tumor occurring frequently during the growth years. It may be found in any of the skeletal segments, and it is often present as an isolated neoformation. In some rare cases it may involve more than one segment or it may be multicentric. The authors report their experience with a case of double localization of metachronous osteoid osteoma.

Bone Neoplasms↗
PubMedDate not supplied

Gorham's disease: a rare case of multicentric localization.

Gorham's disease is described as a rare form of massive non-familiar idiopathic osteolysis with a self-limiting nature, where the simil-angiomatous tissue destroys the bone, that is substituted by fibrous tissue. One case of Gorham's disease is presented, that is interesting because of the sites in which the pathology is localized and because of its multicentricity. The authors reached a diagnosis by carefully studying clinical and laboratory evidence as well as imaging and anatomo-histopathological findings, confirmed by the data reported in the literature.

Arthrodesis↗