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Biomedical subjects

G Specht

Publications and source records attributed to G Specht.

16 recordsLinked to original sources
PubMed1990

[Determination of virus concentration using a minicomputer].

Described in this paper is a physical method by which to determine virus concentrations, including ultracentrifugation of a sample through a saccharose gradient and subsequent analysis of tubule content by means of a flow photometer. Here before, the curves thus obtained used to be graphically evaluated by means of stencil plates. Direct recording and processing of the extinction-time curve by means of a KC 85/1 minicomputer have substantially improved accuracy of results. Time consumption has been reduced, and reading as well as calculating errors have been entirely ruled out. Repetition of determinations confirmed that virus concentrations could be determined at an accuracy of four to seven percent.

Animals↗
PubMed1986

[Surgical indications in small-cell bronchial cancer].

From a total of 1,366 patients with bronchial carcinoma, all selected for an operative procedure, we found 101 patients with small cell carcinoma. For out of 7 of those with small cell carcinoma only mediastinoscopy revealed histological proof of the carcinoma. Thus mediastinoscopy proves to be a valid means for preoperative evaluation of intrathoracic growth of a tumor.

Carcinoma, Small Cell↗
PubMed1983

Comparative light and electron microscopic studies of cystic and papillary tumors of the peritoneum.

Using a cystic lymphangioma of the greater omentum and a benign cystic mesothelioma as examples, the distinguishing characteristics of cystic peritoneal tumors are shown, using light microscopic and ultrastructural findings. A benign papillary mesothelioma is used for comparison. The cellular structures and growth rate of the mesotheliomas are contrasted with the tissue reactions which are typical for irritated serosa. The diffusely growing papillary mesothelioma is a very rare tumor, the cells of which are similar to normal serosa cells, but also show characteristics of other benign or malignant mesothelial tumors and of reactive proliferated mesothelial cells. The diffusely growing benign cystic mesothelioma has only been described in isolated cases and is characterized by cysts grouped in acini with mainly flat, localized cuboidal cell lining. The histochemical properties and cytological findings correspond closely to those of the papillary tumor or normal peritoneal lining cells. In contrast, the cystic lymphangioma probably represents a congenital defect with a slow growth rate. The structure is characterized by a sponge-like arrangement of smooth-walled cysts, in the walls of which smooth muscle cells and lymph follicles are embedded. The endothelium is also flat and ultrastructurally resembles that of lymph vessels.

Adult↗
PubMed1977

[Risks and complications on mediastinoscopy (author's transl)].

Own experiences on 2500 cases of mediastinoscopy. Risks concerning the indication for the mediastinoscopy. Summary of complications with regard to 19 other authors including 12 161 mediastinoscopies. Most appearing complications: Lesions of the nervus recurrens. Lesions of the bigger vessels avoidable by concerning the local anatomy. Recommendations for emergency cases.

Humans↗