[Dentin adhesive resins: new applications and clinical results in conservative therapy (3: Dentin Adhesit adhesive resin)].
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Adhesives↗
Biomedical subjects
G Spina
Publications and source records attributed to G Spina.
Restoration of blood 2,3-diphosphoglycerate levels in multi-transfused patients: effect of organic and inorganic phosphate.
Blood stored in acid-citrate-dextrose (ACD) shows a progressive decrease in 2,3-diphosphoglycerate (DPG) content. Since the decrease in DPG increases hemoglobin oxygen affinity, which in turn may reduce tissue and venous PO2 and peripheral oxygen delivery, many efforts have been made to preserve or restore DPG levels in stored blood. An in vivo rejuvenating technique, employing fructose-1,6-diphosphate (FDP) at a mean dosage of 1 mmol kg-1 day-1 of phosphate, to increase the DPG circulating level in multi-transfused patients is proposed. Eighteen patients, who received at least one-third of their estimated blood volume (3990 +/- 480 (SEM) ml of ACD stored blood) in blood transfusion, were treated: nine with inorganic phosphate, and nine with FDP. Basal DPG was very low in both groups: 12.61 +/- 1.34 (SEM) and 10.42 +/- 0.98 (SEM) mumol g-1, respectively (normal value is 14.5 mumol g-1, at pH 7.40). However, DPG values increased significantly and promptly in patients receiving FDP, whereas in cases of inorganic phosphate administration, it was not significantly raised over the basal value until the third day. Phosphatemia remained normal and constant with FDP, but it rose significantly on the third day of treatment with inorganic phosphate. FDP appears to consistently and rapidly increase DPG levels after transfusion with blood stored in ACD, and to be particularly safe.
2,3-Diphosphoglycerate↗
Evaluation of a test of density-dependence of the expiratory flows in the screening of peripheral airways obstruction.
A test of density-dependence of flow at 50% of vital capacity has been investigated in two groups of subjects (86 in total) in order to evaluate respectively: a) influences that on it may be exerted by altered mechanical properties of the lung in chronic airflow obstruction; b) accuracy and precision of the test in latent and clinical asthma. Lung elastic recoil pressure does not seem to be related to the intensity of density-dependence. Relationships between MEF50 on air and on He-O2, expressed as means of groups allow distinguish between each other, whereas a definite overlap between groups is patent; absolute flows, either on air or on He-O2 are quite satisfactorily reproducible, both in health and disease. Delta% MEF50 shows a good specificity but a poor sensitivity; reproducibility is unacceptable, unless when using on a qualitative scale of figure of 20% as borderline to distinguish subjects responders from non responders.
Airway Obstruction↗