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Biomedical subjects

G Spinetta

Publications and source records attributed to G Spinetta.

6 recordsLinked to original sources
PubMed1991

[Diagnostic considerations in a case of pericardial effusion with anomalous distribution].

The authors report an atypical arrangement of pericardial effusion simulating an expansive mediastinal mass. Radiologic examination of the chest (standard, fluoroscopy and conventional tomography) failed to establish the correct diagnosis, its diagnostic aid was only related to demonstrate the lesion, without provided any additional anatomical and morphological features. The final and correct diagnosis was only obtained with CT and U.S. These latter imaging modalities have correctly located the lesion in pericardial space, and particularly they identified it like an loculated, completely fluid pericardial not corpusculated effusion. The authors remarked the value of CT and US techniques in the study of para and pericardial regions, especially of pericardial serosal surfaces. CT scan allow to localize the lesion, and to discriminate through densitometric values between cystic and solid masses; further more it provided information of possible extracardiac and/or mediastinal invasion. US provides the features of the fluid, its changes during systo-diastolic cycle, its mobility in different patient positions and the thickness of cardial wall. Nevertheless, at present, we consider both imaging modalities indispensable in the study of lesions occupying the cardiac-mediastinal border.

Aged↗
PubMed1989

[The nephrotoxicity of ionic and nonionic contrast media in urography. An evaluation with immunoenzyme technics and monoclonal antibodies].

The nephrotoxicity of ionic and nonionic contrast media (cm) was evaluated in 52 patients undergoing pyelography. The contrast media were i.v. injected in 30'. Urine samples were collected before, 2 and 48 hours after the injection. Urinary albumin (alb) and retinol binding protein (RBP) excretion was evaluated by immunoenzymatic methods; alb and RBP were considered as indicators of glomerular permeability and of tubular reabsorption, respectively. The urinary excretion of brush-border antigen of proximal tubule (BBA) was also measured, as an indicator of microtissue damage, by a sensitive double-antibody ELISA with monoclonal antibodies. The results demonstrate ionic cm to have greater functional effects than nonionic ones, as suggested by the increased urinary excretion of both alb and RBP. However, tubular damage seemed to be more severe with nonionic agents, as suggested by BBA excretion. Although toxic damage had little significance for the patients' health, long-term effects are not to be excluded.

Adult↗
PubMed1987

[Computerized tomography in pulmonary sequestration].

The authors describe two cases of intra and extralobar pulmonary sequestration and evaluate its principal clinical and pathological characteristics. They outline the key role of T.C. in the approach to this pathology. The T.C. enables to collect in a short time a large quantity of useful information for a correct diagnosis which could not be obtained by means of other methods of imaging.

Adult↗
PubMed1985

[CT in the evaluation of the extension of bronchogenic carcinoma].

The computed tomographic patterns in 52 patients with histologically proven lung cancer are reported. The AA. underline the not sobstitutive role of C.T. scan in pre-operative determination of bronchogenic carcinoma extension. C.T. revealed a very high diagnostic accuracy in assessing the primary tumor extension and in evaluating distant macrometastases; however, in showing hilar and mediastinal nodal involvement has not the same accuracy. The AA. think that, at the present time, a combinate C.T. study of the chest, upper abdomen and brain is, in the most number of cases, a rapid, accurate and practical method to evaluate the extension of lung cancer.

Adrenal Gland Neoplasms↗