A chemical adduct of tryptophan and the oncogen 3-acetoxyxanthine.
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Acetates↗
Biomedical subjects
G Stöhrer
Publications and source records attributed to G Stöhrer.
Two-step separation of xanthine derivatives on Dowex-50 utilizing an eluant effect.
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Chromatography, Ion Exchange↗
Correlations between oncogenic and chemical properties of several derivatives of 3-hydroxyxanthine and 3-hydroxyguanine.
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Animals↗
Oncogenic purine N-oxide derivatives as substrates for sulfotransferase.
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Animals↗
Enzymatic O-methylation of N-hydroxyxanthines by a rat kidney enzyme.
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Animals↗
Enzymatic activation of the oncogen 3-hydroxyxanthine.
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Adenosine Triphosphate↗
Synthesis and oncogenicity of 3-hydroxyuric acid.
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Animals↗
Derivatives of 6,6'-bicholestane from cholesterol.
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Chemical Phenomena↗
Oncogenic purine derivatives: evidence for a possible proximate oncogen.
Two additional urinary metabolites of the chemical oncogen 3-hydroxyxanthine are now identified as 8-chloroxanthine and 8-methylmercaptoxanthine. Such products are thought to be derived from a reactive intermediate which can be tentatively considered to be a proximate oncogen. Since each of these 8-substituted xanthines has also been obtained in vitro by reactions of 3-acetoxyxanthine with chloride ion or methionine, their production in vivo can be explained as resulting through the metabolic formation of an activated ester with a reactivity similar to that of the chemical model.
Animals↗
Purine N-oxides. 28. The reduction of purine N-oxides by xanthine oxidase.
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Animals↗
Purine N-oxides. XXVII. The metabolism of guanine 3-oxide by the rat.
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Aminohydrolases↗