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G Stanta

Publications and source records attributed to G Stanta.

At least 73 records · Page 4Linked to original sources
PubMed1986

[Causes of attenuation of the sound waves in neoplasms of the breast. Histologic and echographic correlation study].

The purpose of our study was to compare the ultrasound findings in malignant breast masses (which underwent biopsy) with their histological appearance. In our activity of breast sonography, we observed that the same histological type of breast cancer often shows a different ultrasonic image. The main difference concerns the sonic attenuation or increase through the neoplastic mass. The histological examination took into account the amount of stroma and cells and the architectural pattern of the lesion. Comparing these features with the ultrasonic image, it has been shown that sonic transmission is related more to the architectural pattern than to the fibrous content of the neoplastic tissue.

Breast↗
PubMed1985

Asbestos and tuberculosis in Trieste, Italy.

The distribution of counts of asbestos bodies in lung specimens from 25 persons dying of fibrocaseous tuberculosis was essentially identical to that in age- and sex-matched control subjects. Although tuberculosis mortality has been elevated in the past in cohorts of asbestos workers, asbestos exposure at environmental levels found in a region with a history of heavy asbestos use appears to be unassociated with risk of tuberculosis. Potentiation of the risk of death from tuberculosis may require both a high risk of tuberculosis in the general community and intense personal exposure to asbestos.

Adult↗
PubMed1985

[Uterine metastases of extragenital carcinomas].

Metastasis to the uterus from distant primary neoplasms are rare: this report is an analysis of 20 cases. The primary tumors arose in the breast (12 cases), pancreas (3 cases), stomach (2 cases), lung (2 cases) and gallbladder (1 case). The corpus uteri (and namely the myometrium) is more often involved than cervix. The mean age of the patients is 71 years (range 42-84). Metastases caused abnormal uterine bleeding in only 2 cases; in the others cases no symptoms were observed and so they were unexpected autopsy findings.

Aged↗
PubMed1983

Cancer of the endometrium in the province of Trieste: epidemiological considerations.

The Authors examined the epidemiological behaviour of endometrial carcinoma in the Province of Trieste from 1969 to 1980. In this period a European standard incidence of 14.33(0)/0000 was recorded. The most affected age group is 60 to 69, and the average age is 64 years. A clear increasing trend of this kind of neoplasia was recorded. This increase mainly occurs in younger age groups than those which presently are most affected.

Adult↗
PubMed1983

Invasive cancer of the uterine cervix in the Province of Trieste: epidemiological considerations.

The epidemiological behaviour of the invasive cancer of the uterine cervix in the Province of Trieste is analysed. During this study period, 488 cases of this neoplasia were diagnosed with an incidence rate standardized for the European population of 20.25 degrees/0000. This value is within the average ones recorded in other geographic regions. The age group which is most affected is that from 60 to 64 years. By analyzing the overall incidence rate of the first two years if compared with the last two years of our study period, a 29% decrease is recorded, with an annual average decrease of 2.6%. This value is one of the highest reported in the literature. This decrease is recorded in the age groups over 40, while no decrease is recorded in women under age 40.

Adult↗
PubMedDate not supplied

Morphologic and biologic studies on ten cases of verrucous carcinoma of the vulva supporting the theory of a discrete clinico-pathologic entity.

Ten cases of verrucous carcinoma (VC) of the vulva diagnosed from January 1989 to December 1996 were studied. Patient age ranged from 50 to 83 years. The following examinations were performed on buffered formalin-fixed material: 1). in situ DNA hybridization, probes HPV 6/11, 16/18, 31/35/51; and 2). a series of immunohistochemical stainings to demonstrate wild and mutant types of the p53 protein, cytokeratin expression and pattern distribution (AE1 and AE3), and proliferating pattern (MIB 1). In situ DNA hybridization analysis for human papillomavirus 6/11, 16/18, 31/35/51 was negative in all cases. Wild and mutant types of p53 protein transcribed from related oncosuppressor gene were not detected. Keratins AE1 and AE3 showed a peculiar distribution pattern, that is, AE1 was uniformly positive in the surface and intermediate layers, while it was almost negative in the basal layer which-on the contrary-was mainly positive to AE3 keratins. MIB-1 highlighted 10-40% of proliferating cells; however, in all cases, 70-80% of MIB-1 positivity was found in the basal layer of the neoplastic epithelium. These results seem to show the morphofunctional and growth characteristics of neoplastic epithelium, thus stressing that VC should be considered as a discrete entity in vulvar tumors.

Aged↗
PubMedDate not supplied

[Occupation and lung cancer risk in the province of Trieste: a case-control study].

To investigate the relationship between occupation and lung cancer, a case-control study was performed in the province of Trieste, Italy, where metallurgical and mechanical industries, dock activities and shipbuilding and ship repairing are predominant. Through the local Cancer Registry, pathology records of 938 men who died of primary lung cancer (ICD 162) in a five-year period were examined. Residential, smoking and occupational histories were obtained from interviews of next of kin of 756 cases and 756 age-matched male controls (+/- 2 years). Occupational exposures to lung carcinogens were assessed according to a job-title based approach, identifying industries/occupations with well-recognized lung carcinogen exposures (list A) and industries/occupations with suspected lung carcinogen exposures (list B). Exposure to asbestos was classified as absent, possible or definite. After adjustment for cigarette smoking (four levels) and residence (three levels), a significant association was found between lung cancer and occupations in list A (RR = 2.28, 95% CI = 1.70-3.07) and in list B (RR = 1.33, 95% CI = 1.04-1.71). A significant excess risk was found for workers with definite exposure to asbestos when compared to those with no exposure to lung carcinogens (RR = 1.99, 95% CI = 1.43-2.76). A very high relative risk was observed among heavy smokers with definite exposure to asbestos (RR = 42.8). A stratified analysis showed that the combined effect of asbestos and smoking was compatible with that expected under a multiplicative model. The overall attributable risk in the population (ARp) for cigarette smoking was found to be 87.6%. The ARp fraction for occupations with well-established exposures to lung carcinogens (list A) was 16.2%. The ARp fraction increased to 25.5% (85% CI = 1.4-34.6) when occupations with suspected exposure to lung carcinogens (list B) were included. The ARp fraction for possible or definite exposure to asbestos was 20.1% (95% CI = 11.6-28.6).

Adult↗
PubMedDate not supplied

Incidence of hepatocellular carcinoma in Italy: what could we learn from autoptic studies?

From January 1, 1968 to December 31, 1984, 31,955 autopsies were performed at the Department of Pathology of the University of Trieste. Of these 16,521 were male and 15,434 female which covered about 70% of the population who died in the area over the recent years. Hepatocellular carcinoma (HCC) associated with liver cirrhosis was encountered in 441 cases (380 males and 61 females, M:F ratio 5.8:1) with an overall occurrence of 1.4% in the autoptic population. On the contrary and in the absence of chronic liver disease HCC was only observed in 0.3% of the cases (45 males and 16 females, M:F ratio 2.7:1). Liver cirrhosis accounted for 10% of autopsies (2099 males and 1104 females, M:F ratio 1.8:1). A 15% of cirrhosis was associated with HCC, indicating that major attention should be paid to cirrhotic patients, in particular males after the 5th decade of life. The year distribution of HCC and cirrhosis was fairly constant during the period of time considered. These data suggest that: i) HCC is common in Italy; ii) in the vast majority, HCC occurs in the presence of cirrhosis; and iii) HCC appears to be a rather late disease as it does not reduce the life expectancy of cirrhotic and control populations. Since reliable, nationwide epidemiological data are not available in Italy, it is not known whether these data represent a local realty or whether they may be extrapolated to the entire country. Cooperative and prospective studies appear appropriate in investigating possible geographical differences in HCC distribution and permit a better understanding and prevention of the disease.

Adult↗