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G Steen

Publications and source records attributed to G Steen.

61 records · Page 4Linked to original sources

5-Decynedioic acid, an acetylenic compound in human urine.

An acetylenic dicarboxylic acid, 5-decynedioic acid, has been isolated from human urine. The structure was determined by mass spectrometry of several derivatives, and by infrared spectroscopy. On osmium tetroxide oxidation, a vic-diketone was formed, the mass spectrum of which established the position of the triple bond between carbon atoms 5 and 6. Mass spectrometric evidence for the presence of a small amount of the isomeric 4-decynedioic acid was also obtained. The 24-h excretion of these acids is 0.01-0.1 mmol for healthy adults on a regular diet.

Adult↗

A comparison of cognitive ability in normotensive and hypertensive 68-year-old men: results from population study "men born in 1914," in Malmö, Sweden.

Hypertension and its consequences on cognition was analyzed using data from the study "Men born in 1914" in Malmö, Sweden, a prospective cohort study of cardiovascular disease. The baseline examinations took place in 1982/83 where 500 men participated in extensive medical and social examinations. A neuropsychological investigation was completed including five standardized cognitive tests. The specific purpose of the study was to investigate whether hypertension was associated with cognitive performance. By the use of multiple regression analyses, normal blood pressure and three stages of hypertension were analyzed in relation to test performance. Hypertension Stage 3 was associated with lower performance on tests measuring psychomotor speed and visuospatial memory, whereas hypertension Stage 1 was associated with higher performance on tests measuring verbal ability and constructional ability. The associations were unconfounded by clinical manifestations of atherosclerosis, history of stroke, depressive mood, and antihypertensive drug treatment.

Aged↗

Relationship between MNA and SF-36 in a free-living elderly population aged 70 to 75.

BACKGROUND: Within a larger study of social network and nutrition, we investigated measurements of nutritional status and health related quality of life. OBJECTIVE: To relate a well-established questionnaire of nutritional status (MNA) to a likewise well-established questionnaire of health related quality of life (SF-36) in community dwelling, free-living and, healthy 70-75 years old persons. DESIGN: Before an interview, the MNA and SF-36 questionnaires were filled in by 128 participants from a sample of 262 subjects. RESULTS: The MNA worked well as a measurement in this sample. Many MNA aspects correlated with the SF-36 scales. The correlations between MNA total score and the eight SF-36 scales varied from .27 to .62. DISCUSSION: This correlation was partly due to the fact that MNA has questions of health but also to the fact that there is an empirical relation between nutrition and health. CONCLUSION: The MNA measurement is applicable to a healthy, free-living elderly population and parts of the MNA can be interpreted as measurements of health related quality of life. Low values of SF-36 could also be used as predictors of risk of malnutrition, although further studies are required to confirm this result.

Activities of Daily Living↗