PubMed HealthSearch

Biomedical subjects

G Stickrod

Publications and source records attributed to G Stickrod.

4 recordsLinked to original sources

Fetal brain implants improve maze performance in hippocampal-lesioned rats.

Hippocampal tissue from day 16 fetal rats was implanted into the damaged hippocampal formation of adults. Significant recovery of the lesion-induced deficit in spatial maze performance was observed, particularly in those animals which showed integration of the implanted fetal tissue with the host hippocampal formation. A two-stage procedure in which 2 weeks or more elapsed between the initial lesion and the implantation resulted in more successful tissue integration and better behavioral recovery.

Animals

Ketamine/xylazine anesthesia in the pregnant rat.

Pregnant albino rats were anesthetized with a combination of ketamine and xylazine. A minimal effective dosage of 90 mg/kg for ketamine and 10 mg/kg for xylazine provided satisfactory anesthesia in 92% of the subjects, without adverse effects on gestation or the fetuses.

Anesthesia

A versatile primate cage for a multiple use facility.

A mobile-transport-squeeze cage for primates was constructed. The cage contained a clear plastic guillotine door, squeeze apparatus, ventilation holes and locking casters. The squeeze apparatus could be operated by one person.

Animals