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Biomedical subjects

G Stolze

Publications and source records attributed to G Stolze.

7 recordsLinked to original sources
PubMed1991

[Use of a computer in a clinical-toxicological laboratory with a fuzzy search].

If a clinician is faced with acute intoxications a rapid toxicological test is essential. The toxic substances are identified by a combined use of various systems of analysis such as gas chromatography, thin-layer chromatography or UV-spectroscopy. As the result of the analysis a data pattern is obtained which can be interpreted by comparing it with substance-related reference patterns. This paper describes a computer-program which allows more efficient reference comparisons and which gives a support of the decisions. The algorithms of the comparisions are based on fuzzy-theory.

Diagnosis, Computer-Assisted↗
PubMed1989

[The cito-laboratory information system CILIS].

The cito-laboratory of a big hospital must be able to work a higher number of cito-analyzes economically and with a high degree of security and to send back the results as fast as possible to the demander. For that reason the simple employment of efficient analytical methods or tools is not sufficient. The cito-laboratory-information-system CILIS is able to support all the steps of work, which are necessary to workout cyto-results and to send them back to the demander. It is also able to relieve the nurses as well as the MTLA from writing and recording. CILIS is based on the computer A 5120. It is usable in other comparable institutions and with certain restrictions to further development or enlargement. In our hospital the system has been working since november 1986 during the regular shift and the shift from 2 pm till 10 pm and partly on working days from 10 pm to 7 am and respectively at the weekend. Since that time it has been approved excellently.

Germany, East↗
PubMed1988

[Renal actions of bendamustin (Cytostasan) in rats].

In adult rats influences of single doses of bendamustin (0.5, 1 or 5 mg/100 g b.wt. i.p.) on kidney function were measured (time of experimentation 8 d following administration). Bendamustin administration is followed by an increase of kidney weight caused by a higher water content of kidney tissue. An increase of plasma concentrations of creatinine and of urea following bendamustin (1 or 5 mg/100 g b.wt. i.p.) indicates a reduced excretion capacity of kidney. Bendamustin administration is not connected with a distinct proteinuria. The highest administered does (5 mg bendamustin/100 g b.wt. i.p.) caused an oliguric effect connected with a distinctly reduced renal excretion of osmotically active substances. There is a distinct diminution of renal excretion of sodium following bendamustin administration and a decrease of renal excretion of PAH can be stated. It is most likely that bendamustin can reduce the glomerular function: Following administration of 1 mg bendamustin/100 g b. wt. i.p. CIn is reduced whereas a statistically significant increase of tubular transport capacity for organic anions can be measured (TmPAH).

Animals↗
PubMed1975

[Scientifically proved emergency examinations in clinical laboratory].

The most clinical laboratories may guarantee the laboratory diagnostic service out of regular laboratory hours only in a limited extent. In order to guarantee the short-term performance of emergency examinations with a security of the results which is to be compared with the daily routine, therefore, a selection of parameters must be carried out, which satisfies the demand of the clarification of suddenly occurred life-threatening conditions and possibly also of their control of therapy. It is presented a maximum program of parameters, which must be on principle, at the disposal of the suitable medical care of men in acute emergency situations within a territorial organisation.

Appendicitis↗
PubMed1975

[Consequences of the daily rhythm of organ functions and of metabolic processes for screening].

The effects of the influencing factors such as age, sex, exposition to pharmaca, physical activity, alimentary load and endogenic daily rhythm on sensitivity and specifity of the parameters of screening are briefly described. It is reported on the results of examinations of one of these influencing factors and on the endogenic daily rhythm with the help of selected instances.

Adult↗