Biomedical subjects

G Strutton

Publications and source records attributed to G Strutton.

6 recordsLinked to original sources

PubMed1991

Squamous cell carcinoma arising in a case of vulvitis granulomatosa or vulval variant of Melkersson-Rosenthal syndrome.

A case of vulvitis granulomatosa or the vulval variant of Melkersson-Rosenthal syndrome (MRS) in a young adult patient with systemic lupus erythematosus is presented. She also had evidence of cervicovulvovaginal human papilloma virus (HPV) infection. Nine years later she developed a squamous cell carcinoma (SCC) of the vulva. HPV 6/11 was found by DNA in situ hybridization within a vulval condyloma as well as within the carcinoma. This case is unusual in that SCC associated with HPV 6/11 developed in her vulva affected by MRS rather than in the cervix, where SCC was more likely to occur considering this patient's age.

Adult↗

PubMed1989

A report of actinomycosis involving the lung and liver.

A case is presented of actinomycosis that involved the lung and the liver, which was diagnosed after a computed-tomographic-guided needle biopsy of a liver mass. The diagnosis was made on histological grounds that were based on the staining and morphological characteristics of Actinomyces spp. Imaging techniques suggested a communication between the lung and liver lesions. The regression of the disease was followed during 12 months of therapy. The patient remained free of disease for three months after the cessation of treatment. The relevant literature is reviewed.

Actinomycosis↗

PubMed1988

Cutaneous light microscopic and ultrastructural changes in a fatal case of jellyfish envenomation.

A 5-year-old male suffered fatal envenomation from a jellyfish subsequently identified as Chironex fleckeri. Contact with the tentacles of the jellyfish had produced characteristic whiplash-like weals on the skin. At autopsy, skin from these areas was taken and later studied by light microscopy and electron microscopy. Both studies identified numerous nematocysts penetrating the epidermis and papillary dermis in the region of the sting.

Animals↗

PubMed1988

The Martin Titanline arterial clamp. A new lightweight alternative.

When haemostatic clamps are applied, evidence of injury at the site of clamp application may be seen when the clamp is removed. Rarely, the intima may be disrupted. When a new arterial clamp became available, a study was designed to compare the Martin Titanline arterial clamp (13-143-35, curved arterial clamp) with several other arterial clamps already in use. The Martin clamp is a modified pivot-point, preset-tension, spring-controlled arterial clamp. The closing pressures of several clamps were measured objectively. The injury produced when the clamps were applied to occlude the blood flow on the carotid artery of a dog was assessed by histological study of the excised segments of the arterial wall. Histological cross-sections were prepared from canine carotid artery which had been perfused for 1 h after the clamp had been applied for 1 h. Histological evidence of injury was limited to disruption of the intimal layer and compression of the medial layer. No significant difference between the amount of damage caused by the DeBakey, Satinsky or Martin clamp was identified. When compared to the other varieties of clamp listed above, the Martin clamp had a significantly lower closing pressure (304 g) compared with 580g (Bulldog), 580 g (Satinsky), and 686 g (DeBakey). The Martin clamp was easier to apply, did not obstruct the operative field as readily and had good clamp-retention characteristics throughout the procedure.

Arteries↗

PubMed1987

Transferrin receptor expression by human bladder transitional cell carcinomas.

The expression of transferrin receptors (TFR) by normal and neoplastic urothelial cells was studied in "control" patients and in patients with transitional cell carcinoma of the bladder. These tumours were graded independently and consisted of 19 grade I, 30 grade II and 19 grade III lesions. TFRs were identified using a monoclonal antibody specific for TFR (OKT9) in an immunofluorescent or avidin/biotin-immunoperoxidase technique on fresh frozen sections. TFRs were not detected on normal urothelium. However, positive staining was found to increase with increasing pathological grade and stage of the tumours, ranging from 31.6% of grade I to 78.9% of grade III tumours and 51.2% of pTa (mucosa only lesions) to 87.5% of pT2/pT2+ (muscle invasion +/- deeper) primary urothelial malignancies.

Adult↗

PubMed1987

Acro-angiodermatitis. A simulant of Kaposi's sarcoma.

Acro-angiodermatitis, usually related to venous insufficiency of the lower limbs, may simulate some of the features of Kaposi's sarcoma, both to the clinician and the dermatopathologist. With the increasing incidence of Kaposi's sarcoma related to the acquired immune deficiency syndrome (AIDS), there is a greater awareness of Kaposi's sarcoma than the benign simulant. Against this background, there is a danger that acro-angiodermatitis will be misdiagnosed as Kaposi's sarcoma.

Acrodermatitis↗