Biomedical subjects

G Stuhldreier

Publications and source records attributed to G Stuhldreier.

3 recordsLinked to original sources

PubMed1991

[Results of organ saving splenic surgery].

The charts of the 24 patients we treated in the past 7 years with spleen conserving methods after trauma and of the 13 patients we treated with splenic autotransplants were reviewed for this study. The results demonstrate, that the conservation of an injured spleen, desirable in adults too, is possible in appropriate cases without greater risk. Infrared coagulation and fibrin sealing proved as safe techniques, that can be augmented by others. Patients with subcapsular hematomas of the spleen can be left normally without operation in absence of other intraabdominal injuries; in these cases meticulous surveillance with the possibility of operations and ultrasound examinations at any time is necessary because of the risk of delayed bleeding. In the meantime we gave up the autotransplantation of splenic tissue after splenectomy for complications and doubts in the efficiency.

Adolescent↗

PubMed1989

[Observations on post-traumatic osteitis].

The following study reports the frequency, the promoting factors, the therapy and her results of the 32 patients with posttraumatic osteitis we treated between 1984 and 1986 in the Surgical University Clinic Tübingen. Most of the primary injuries were caused by traffic-accidents; especially dangerous were those with motor-bikes, which led frequently via open fractures of the shank to osteitis. We saw the highest infection-rates after plate-osteosyntheses. The infects became obvious in most cases either about one month after the accident or a year later coinciding with the increased use of the limb. The most frequent bacterium was Staph. aureus both in the mono-infections and in the mixed-infections forming a third of the group. We always performed an operative therapy with the intention to stabilize the bone and to clean the infection-site. The strict performance of this management led to infect-suppression in all cases with the need of only one amputation.

Adult↗

PubMed1988

Continuous or bolus chemotherapy with 5-fluoro-2'-deoxyuridine in transplanted experimental liver tumors?

The effect of continuous and discontinuous locoregional chemotherapy with Floxuridine (FUdR) was studied in a standardized and controlled animal model, using the transplantable Novikoff hepatoma in Sprague-Dawley rats. The liver was perfused after transplantation with a total of 420 mg/kg FUdR, via a fully implanted osmotic minipump or miniport and catheter in the hepatic artery, either continuously (n = 22) from day 5 to day 12, or discontinuously (n = 28) on days 5 and 8. Viable tumor volume and peritumorous cell infiltration were measured. No reduction in tumor volume was attained using discontinuous therapy, in contrast to a highly significant reduction using continuous therapy (P less than 0.001). Significantly less cell infiltration was found after discontinuous than after continuous therapy. In conclusion, continuous locoregional chemotherapy with FUdR was the superior administration method on measurable tumor effect, when compared to discontinuous infusion.

Animals↗