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Biomedical subjects

G Szappanyos

Publications and source records attributed to G Szappanyos.

9 recordsLinked to original sources

[Comparative study of sequential analgesic anesthesia (SAA) with continuous-infusion analgesia by fentanyl].

A group of elderly (mean age: 75 years) patients undergoing a prothetic on the hip under analgesic anaesthesia using fentanyl by continuous infusion (7 micrograms.kg.h(-1)) was compared with a similar group receiving sequential analgesic anaesthesia using fentanyl (25 micrograms.kg as a bolus then 7 micrograms.kg(-1).2030mins(-1)). Comparison of the results obtained revealed a variation in mean cardiocirculatory parameters which was less marked in the group receiving fentanyl by infusion than in the group receiving it sequentially. The higher doses used in the sequential analgesia group led in the majority of cases to severe respiratory depression requiring its reversal by an antagonist or postoperative ventilatory assistance, whilst the use of fentanyl by infusion made it possible to reduce total doses of the drug and ensure adequate spontaneous respiration at the end of the operation.

Aged↗

[Present role of selective intubation sounds in thoracic surgery].

After the indications for selective bronchial intubation, the methods of bronchial control by various techniques, together with their advantages and disadvantages, are discussed. A Advantages: -the right and left lungs are completely separated and if the tube is correctly placed in position, it will avoid any loss of secretions towards the healthy lung; -the lungs may be ventilated together or separately; -there is perfect water tightness within the traches and bronchi; -rapid deflation or inflation of each may be obtained without modifying the position of the tube. B Disadvantages: -there is an increased resistance to the air flow if only one lung is ventilated; -alone, a small diameter aspiration catheter may be used; -the catheters are costly, they may be difficult to introduce in small size subjects.

Bronchial Diseases↗

[Clinical investigations of the steroid anaesthetic agent CT-1341 (Althesin) (Cardiovascular and respiratory effects)].

The new steroid anaesthetic CT-1341 (Althesin) has been used as an induction agent in dose of 0.07 ml/kg body weight. Following injection, stage 1 anaesthesia is reached in an average of 30 sec with a clinical duration of between 12 and 20 min with total recovery, supported by a normal pre-anaesthetic EEG tracing, in 40 to 50 min. The respiratory depression following injection in characterized by a short period of apnea followed by an increased respiratory rate and a diminished tidal volume; there is a decrease of the pO2 of about 15%, but the pCO2 and pH values do not show significant variations. Concerning its action on the cardiovascular system, there was found an increase of heart rate (+14%), a decrease of both systolic (-19%) and diastolic pressures (minus decrease of both systolic (-19%) and diastolic pressure (-13.5%), central venous pressure and the peripheral vascular resistance (-14%) with hardly any change in the pulmonary artery pressure.

Adult↗