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Biomedical subjects

G Szikla

Publications and source records attributed to G Szikla.

At least 37 records · Page 2Linked to original sources
PubMed1977

Interstitial gamma irradiation by 198Au of the pituitary in diabetic retinopathy. Selective growth hormone blockade and ocular results.

Pituitary interstitial irradiation by stereotaxic implantation of a gamma pointemitter was performed in 110 patients with progressing diabetic retinopathy. Reduction of growth hormone secretion peaks was delayed, but was consistent and selective in all cases controlled by somatotropin stimulation test, while other pituitary secretions remianed unchanged in all but five cases. In 31 patients who had no associated photocoagulation, long-term postoperative assessment showed significant improvement of hemorrhages and intrarentinal new vessels with preservation of visual acuity. Preretinal vascular proliferation (except when treatable by photocoagulation), extensive retinitis proliferans, and macular deterioration are contraindications. This technique represents a new approach in the functional pituitary neurosurgical treatment of diabetic retinopathy and differs from all other procedures that result in a more or less complete hypophysectomy.

Body Weight↗
PubMed1975

In vivo localization of brain sulci by arteriography: a stereotactic anatomoradiological study.

The authors studied the course of the cortical arteries using the Talairach stereotactic system (orthogonal 4.8 m teleradiography, with rigid fixation of the skull in the stereotactic frame) in both anatomical specimens and normal bilateral carotid angiographies of epileptic patients. Anatomoradiological correlations between arterial patterns and underlying brain surface were identified by detailed 3-dimensional analysis of brain-skull preparations, where gyri and injected arteries were dissected progressively with stereotactic X-ray and photographic pictures taken at each step. The vascular landmarks so identified were studied in stereoscopic arteriographies that give a direct visualization of the spatial relationships of the arterial tree moulding the cortical surface thus allowing the recognition of the localization of the principal gyri and sulci. The latter were drawn on stereotactic diagrams. The basic sulcal pattern as shown by the arteries is strikingly symmetrical in both hemispheres of the same individual, in spite of variability in branching of the arterial tree. The disposition of the vascular landmarks in the retroinsular region reflects the left-right asymmetry of the planum temporale that can be recognized in vivo. This can give a clue to the study of anatomofunctional correlations with regard to speech dominance. A limited first series studied in this respect strongly suggests a close relationship between anatomical and functional asymmetry of the human cerebral hemispheres. Generally speaking, the authors feel that 3- dimensional, anatomical interpretation of angiography permits a direct localization of brain structures including the cortex, that can be used instead of indirect localization landmarks in stereotactic explorations, and further, that the wealth of anatomical information that can be drawn from angiography with their method may be helpful in diagnosis or for planning surgery.

Cerebral Angiography↗
PubMed1975

Clinical note: clinical and tele-stereo-EEG findings in a patient with psychomotor seizures.

A patient was studied who had posttraumatic epilepsy with adversive, psychomotor, and grand mal seizures. During tele-EEG recording from depth electrodes, 4 psychomotor seizures were accompanied by discharge originating in the frontal lobe. The patient sometimes could recall his behavior and believed it to be voluntary. Amnesia was more apt to be total after the seizure than during it.

Adult↗