[A NEW MUCOPOLYSACCHARIDE FROM ENTEROBACTERIA].
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to G T BARRY.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
All acidic carbohydrate has been isolated from the culture medium of the enteric microorganism E. coli K(235) L(+)O. This substance has been named colominic acid. N-acetylneuraminic acid, which has been isolated from the hydrolysate of colominic acid, is believed to be the monomer unit from which colominic acid is constituted. Colominic acid is not antigenic in rabbits. Tests have failed to reveal a relationship between the ability of E. coli K(235) to elaborate colominic acid and its virulence in mice.
By chemical fractionation a substance having colicine K activity has been obtained from the culture medium of E. coli K(235) L(+)O. Colicine K activity was found associated with the O antigen of this microorganism. When the O antigen was dissociated, colicine K activity remained with the protein component of the antigen.
Explore the source record for details and available documents.
An apparatus for maintaining the pH of an actively growing bacterial culture at constant level has been described. Using this apparatus it has been shown that the production of maximal amounts of colicine K from a strain of E. coli known as K235 is dependent upon an enriched nutrient medium which is maintained at pH 7.0.
The development of viral neutralizing antibodies in animals injected with T(3) or T(4) phage is considerably inhibited by the presence of bacterial antigens. A new procedure has been described to liberate phage from infected E. coli B bacteria by inducing lysis with penicillin. By immunological means it has been shown that T(4)-infected cultures of E. coli B, in which phage development has been inhibited with proflavine, contain the viral neutralizing antigen after lysis. In contrast, it has not been possible to demonstrate by immunological means the appearance of viral neutralizing antigen in E. coli B infected with T(3) prior to the appearance of intracellular phage.
A study has been made of the effect of bactericidal agents on the phage adsorption properties of Phase II. Sh. sonnei. The ability of this microorganism to adsorb T(3), T(4), and T(7) phages can be altered by treating the bacteria with chemical and physical agents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.