Biomedical subjects
Publications and source records attributed to G T Basinger.
Eleven patients with urologic cancer had an abnormal 99mTc (technetium-99m) bone scan as the sole evidence of metastatic disease. Potentially curative therapy should not be withheld on the basis of a "positive" bone scan if such an area is accessible to selected bone biopsy and proves to be negative for tumor histologically.
Three cases of lymphocysts occurred in a series of 97 patients undergoing extension pelvic urological operations, an incidence rate of 3.1 per cent. This is the first report of this complication after urological lymphadenectomy. Awareness of the entity is important to urologists since lymphatic staging operations for prostate and bladder carcinoma are widely used to help plan definitive therapy. Athough this complication is rare after renal transplantation it may cause significant interference with graft function. The etiology, symptoms, findings, diagnosis and treatment of this condition are reviewed. Echography is presented as an ideal technique to diagnose the condition and to guide in its management.
The Snell dwarf mouse (dw/dw) is the result of a single recessive gene that is not sex-linked. The dwarfism is caused by the congenital deficiency of growth hormone, thyrotropin, and prolactin. This unique genetic model was selected to study compensatory renal hypertrophy. Compensatory renal hypertrophy occurred to a significant degree (P less than 0.01) in the unilaterally nephrectomized dwarf mutant (dw/dw), normal heterozygous (dw/DW), and normal homozygous (DW/DW) male littermates. There was no significant difference in the amount of compensatory renal hypertrophy between the groups (P greater than 0.5). These results suggest that three of the anterior pituitary hormones are not necessary for the compensatory hypertrophy response to unilateral nephrectomy.
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