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Biomedical subjects

G T Chkuaseli

Publications and source records attributed to G T Chkuaseli.

7 recordsLinked to original sources

[Case of simultaneous operations of aortocoronary shunt and panhysterectomy].

Simultaneous operations on different organs and cavities, including urgent and scheduled operations, always are associated with high risk of operative and postoperative periods. The case of simultaneous operation of aortocoronary shunt and panhysterectomy is presented in the paper. In the case of our patient despite the severe condition: occlusion of left anterior descending coronary artery (rest and effort angina) and endometrium malignant tumor worsened by concomitant pathologies including bronchial asthma, hypothyreosis, pyelonephritis and obesity, the surgical intervention was completed successfully without complications at operational and postoperational periods.

Angina, Unstable↗

[Radiation-induced multiple tumors].

Multiple primary tumors have been detected in 192 (5.0%) cases out of 3,812 patients with primary cervical malignancies, 100 (2.6%) cases having been traced to radiation-related origin. The peculiarities of the syndrome of radiation-induced multiple tumors of the rectum, vagina and corpus uteri, duration of their development, histological patterns, degree of cell differentiation, depth of invasion and patterns of metastasis spreading have been identified. Relative cumulative risk of secondary tumor development and causal factors have been established.

Female↗

Geographic peculiarities of endometrial and cervical cancer incidence in five continents (review).

The review of references and data on endometrial and cervical cancer incidence in five continents (1970, 1976, 1982, 1987) are presented. The increase in cervical cancer rates in the developing countries of Asia, Africa and Latin America has been recorded. The hormonedependent tumours (endometrial, breast cancer) prevail in the economically developed countries of Europe and North America. They have shown a tendency to increase since the end of the 70's. The possible causes of peculiarities in oncogynecological incidence have been discussed.

Africa↗

[Treatment of patients with vulvar cancer].

Data concerning patterns of dissemination and recurrence as well as the end results of treatment of 148 cases of vulvar cancer were used to develop adequate therapeutic options for the disease versus age and extent of tumor. Prophylactic and therapeutic removal of the inguinal and femoral lymph nodes, high radicality of vulvo- and lymphadenectomy, and fast electron irradiation assured a better prognosis.

Adenocarcinoma↗

Treatment planning in vulvar cancer patients.

Peculiarities of metastatic spread, recurrences and treatment results were studied in 148 vulva cancer patients, indications to adequate treatment were specified with respect to age, local and regional tumour spread. Efforts to apply on a wider scale preventive and therapeutic removal of inguinofemoral lymph nodes, to make vulvectomy and lymphadenectomy more radical, employment of radiotherapy with fast electrons lead to a substantial improvement of prognosis.

Combined Modality Therapy↗

Optimal version of I and II stages vulvar carcinoma--surgical treatment.

In gynaecological clinic years during 1970-1986, 270 vulval carcinoma patients (I stage 12.6%; II 50.3%; III 29.3%; IV 7.8%) underwent treatment. 34.8% patients age was 60-69, 32.2% 70-79. Average age 66 years. In 70% patients diagnostic epidermoidal, 22.2% low differentiated cancer and 1 case (0.4%) adenocarcinoma. 187 patients underwent total vulvectomy (additional telecurie therapy 18 patients, 2 chemotherapy), 54 total vulvectomy + regional lymphadenectomy, 29 chemo (6), radio (3), symptomatic (20) therapy. 5-year recovery generally equated 40.1% (vulvectomy + lymphadenectomy 58.4%; vulvectomy only 35.8%), at I-II stage 52.1% (vulvectomy + lymphadenectomy 85.7%; vulvectomy 50.0%), at III stage 11.4% (vulvectomy + lymphadenectomy 42.9%; vulvectomy 6.7%), at IV stage 0%. T1 regional lymph nodes involvement, clinical signs (N1, N2, N3) were present in 24.1% patients, T2 36.1%, T3 70.8%. Out of marked 92 patients, lymphadenectomy was performed in 54, mainly with T1 and T2. Histological metastases observed in 48.1%, i.e. no more than 14% T1 and T2 patients. Considering the above raised question rised - it is justifiable in I and II stage patients with negative lymph nodes, regarding advanced age and concomitant diseases, perform protracted traumatic operation. But without histology it's hard to decide lymph nodes condition. Taking into account certain stage characteristic of metastatic spreading, in our clinic from 1985 in T1 and T2 vulval carcinoma without (N0) and/or with (N1, N2) regional lymph nodes involvement signs modified less traumatic one stage extensive vulvectomy with bilateral inguinal lymphadenectomy is performed. Suboperational morphological (cytology, histology) lymph nodes study is conducted. Upon metastases discovery dissection is carried out on femoral lymph nodes as wall.(ABSTRACT TRUNCATED AT 250 WORDS)

Adenocarcinoma↗