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Biomedical subjects

G T Chua

Publications and source records attributed to G T Chua.

At least 19 recordsLinked to original sources

Stone surface area determination techniques: a unifying concept of staghorn stone burden assessment.

The use of stone surface area measurements obtained from standard radiographs provides a more accurate and reproducible assessment of stone burden when reporting results and treatment recommendations for staghorn calculi. Techniques for determining stone surface area include use of graph paper, planimeter or computerized image analysis. The use of graph paper is inefficient while planimeters suffer from significant variation for areas less than 500 mm.2 (more than 5%). Computer image analysis is accurate, rapid and easiest to perform. Software programs compatible with microcomputers are readily available making assessment of stone surface area practical and inexpensive. Stone surface area showed close correlation to stone volume as measured by 3-dimensional computerized tomography (correlation coefficient 0.84, p = 0.005). Stone surface area determination enables more accurate reporting of treatment results and, thus, recommendations based upon stone burden. Comparison of data between institutions becomes more meaningful if stone surface area is used. Stone surface area also provides a useful basis to study and compare trends of treatment within a single institution.

Humans

Uterine adnexal torsion: a case report.

Uterine adnexal torsion is a surgical condition that requires prompt diagnosis and intervention. An ultrasound examination demonstrating a unilaterally enlarged, hypoechoic ovary with several small spherical, peripherally located sonolucent structures in the involved ovary, in addition to a history and physical consistent with torsion, confirms the need for surgical intervention. In this article, we present a case of uterine adnexal torsion and discuss the etiologic, diagnostic and therapeutic aspects of this entity.

Adult

The accuracy of preoperative staging for surgically resected laryngeal cancer.

A retrospective analysis was undertaken to evaluate the accuracy of preoperative staging for laryngeal cancers. T (primary tumor) stage was evaluated more accurately by the combined assessment (clinical examination plus computed tomography (CT) for all laryngeal tumors when compared to the clinical examination (75% versus 31%, p less than 0.04). Supraglottic tumors were evaluated more accurately by CT than the clinical examination (86% versus 0%, p less than 0.01). There was no difference between CT and the clinical examination when evaluating glottic and transglottic lesions. The clinical examination, CT and combined assessment equally evaluated N (regional lymph node involvement) stage. The clinical examination and CT are complementary exams that should be used in conjunction when evaluating patients with advanced laryngeal cancers.

Humans

Calcific deposits in the heart.

Four case reports are presented which illustrate various patterns of calcific deposits in the heart. Valvular, myocardial, intracavitary, and coronary calcific deposits are illustrated, with emphasis on pathology and clinicopathologic-radiologic correlation. "Dystrophic" and "metastatic" calcifications are terms used to describe calcific deposits in abnormal and normal soft tissues, respectively. These terms are somewhat confusing in relation to the myocardium, however, as the chronologic sequence of cardiac injury is often uncertain. We suggest that these terms be avoided in relation to the heart, in favor of simple descriptive terms such as "myocardial calcific deposits." Many conditions, such as renal failure and hypercalcemia may contribute to the likelihood of soft tissue calcification, although a definite common etiology has not been identified. Likewise, soft tissue calcification has been difficult to diagnose premortem. The advent of ultrafast (cine) computed tomography may provide a quick, noninvasive, highly sensitive and specific method for diagnosis of soft tissue calcific deposits in the future.

Adult

Nonfunctioning paraganglioma of the liver, gallbladder and common bile duct.

Paragangliomas are rare extra-adrenal neoplasms of neural crest origin. Although most of these lesions are of retroperitoneal origin, paragangliomas have been reported at a host of remote sites, including the urinary bladder, larynx, orbit and lung. In our review of the literature, we discovered only solitary case reports of such neoplasms involving the gallbladder and hepatic duct. We report a case of paraganglioma simultaneously involving the liver, gallbladder and common bile duct, as well as celiac and portal lymph nodes. Our findings add paraganglioma to the list of differential diagnoses for hypervascular portacaval space lesions. Furthermore, the radiographic appearance of this unusual tumor may be sufficiently distinctive to suggest the correct histologic diagnosis preoperatively.

Cholangiopancreatography, Endoscopic Retrograde

Traumatic knee injuries: the accuracy of MRI compared with arthroscopy.

Forty-three knees in 43 patients were evaluated preoperatively with magnetic resonance imaging (MRI). Both menisci and cruciate ligaments subsequently were examined directly with arthroscopy. A grading scale was used to evaluate intrameniscal signal intensity and to predict the presence of meniscal tear using MR. Compared with arthroscopy, the sensitivity, specificity and accuracy of MRI were, respectively, 100%, 88% and 93% for tears of the medial meniscus; 72.7%, 93.7% and 88.4% for tears of the lateral meniscus; 100%, 96.7% and 97.7% for tears of the anterior cruciate ligament. There were no posterior cruciate ligament tears, and none were suggested from the images. Our results show that MRI is a valuable diagnostic aid in the management of traumatic knee injury.

Adolescent

Liver transplantation.

A multidisciplinary approach is necessary in addressing the needs of a patient with end-stage liver disease. The development of the liver transplant program at MHI was a natural extension of the transplant and critical care programs already in place. The case report described exemplifies that valuable input from ancillary support groups is necessary for a successful liver transplant program. Experience gained in the area of liver transplantation not only benefits liver transplant patients but also extends to other areas of clinical medicine. One year ago, an Indiana resident had to travel out of state to receive this specialized form of care. Today this is no longer the case.

Humans

Ultrasound guided drainage of pleural fluid.

Ultrasound guided drainage has been reported as a highly successful drainage procedure. Computed tomography (CT) and fluoroscopy also have been cited as favorable imaging modalities for the treatment of pleural effusion. With its extreme sensitivity to fluid collections and rapid and accurate localization of fluid, real-time ultrasound has become the primary imaging modality for the interventional drainage of pleural fluid. This is a retrospective study of patients with radiographically suspected pleural effusion, using ultrasonic scanning for possible drainage. A special bedside drainage technique in critically ill patients also is described.

Drainage

Sonography of appendiceal intussusception.

A case in which appendiceal intussusception was diagnosed preoperatively by sonography is described. The sonographic finding of multiple concentric hypoechoic and hyperechoic rings was confirmed at laparotomy to be due to appendiceal intussusception. Demonstration of the sonographic coiled spring sign in the right lower quadrant should raise the possibility of appendiceal intussusception. The differential diagnosis is discussed.

Adult