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Biomedical subjects

G T Garyfallou

Publications and source records attributed to G T Garyfallou.

4 recordsLinked to original sources

Two siblings poisoned with diphenhydramine: a case of factitious disorder by proxy.

We report a case of factitious disorder by proxy (FDBP), formerly known as Munchausen syndrome by proxy, in which 2 siblings were poisoned with diphenhydramine. Although diphenhydramine is a readily available medication, no report of its use as the sole agent in an FDBP case was found in a literature search. Although sibling involvement in FDBP is well documented, this is the first case report of 2 siblings hospitalized simultaneously because of intentional poisoning with the same substance. Finally, the use of physostigmine to definitively diagnose anticholinergic poisoning in a case of FDBP has not previously been described.

Antidotes↗

Mycobacterial sepsis following intravesical instillation of bacillus Calmette-Guérin.

Intravesical bacillus Calmette-Guérin (BCG) administration for bladder cancer may lead to BCG dissemination in the compromised host. A case of a 63-year-old man with shock secondary to BCG sepsis is reported. The recognition and treatment of disseminated BCG infection are discussed. In addition to standard therapy for urosepsis, early therapy with steroids and coverage with antitubercular medications should be initiated for patients with this condition. In general, the author recommends that all febrile patients who have received BCG immunotherapy within three years, and who have no obvious source for their fever, have acid-fast bacilli blood cultures done for Mycobacterium bovis, and that these patients be admitted to the hospital for further evaluation.

Administration, Intravesical↗