Biomedical subjects
Publications and source records attributed to G T Haneveld.
A 23-year-old man died from the pulmonary manifestations of cardiac angiosarcoma. The absence of all cardiac signs and symptoms was an unusual feature. The clinical outcome was rapidly fatal. Apparently, the presence of cardiac symptoms in a patient with primary cardiac angiosarcoma is not obligatory.
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Pott's disease, i.e. caries of the spine with gibbosity, psoas abscesses and palsy, has been known since antiquity, its relation with tuberculosis suspected, as is seen in the Hippocratic writings. In the 18th century cases were studied in France and England; in the Netherlands by Hovius, Camper, Bonn and Coopmans. The most lucid descriptions however were those of SIR PERCIVALL POTT (1779). An annotated Dutch translation by DU PUI (1779) called attention to the treatment of this disease which was on the increase. In retrospect the eponym 'Pott's disease' seems well deserved.
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An 87-year-old woman presented with a rapidly growing tumour at the nasal side of the upper eyelid. The clinical diagnosis was basal cell carcinoma. During surgery, the impression of malignancy was accentuated by the finding that even the conjunctiva had been invaded. Histological examination revealed an eccrine acrospiroma with, indeed, many mitoses but, on the other hand, a completely benign aspect. Besides, there was no recurrence after 1 year.
Compression in medicine goes far back in history. In ancient Rome and during the Renaissance compression by means of leaden plates was a well-known treatment of cancer. Compression flourished particularly in the first half of the 19th century, in Great Britain encouraged by the publications of Young and Arnott and Walshe, in France especially by the work of Récamier. Around 1850 this treatment fell into discredit: on the one hand because of improved surgical possibilities, on the other because not all the alleged cures concerned true malignancies. The results were, on the whole, disappointing. Quite recently, compression re-appeared as a treatment of carcinoma of the urinary bladder.
Long before De la Peyronie's description of three cases of plastic induration and curvature of the penis (1743) the disorder was already known. The Ephemerides (1687) and the rather scabrous booklet, Venus minzieke gasthuis (Venus Hospital for the lovesick)(1688), contain short remarks on this condition. Two extensive Dutch contributions -- not mentioned in the literature on this subject -- were written by Nicolaas Tulp (1593--1674) and Fredrik Ruysch (1638--1731). The first one is a case history, the second one is more general discussion with a fine engraving added. Treatment varied according to the various early authors. The therapeutic successes claimed must be seen in the light of the natural history of this disease: spontaneous improvement occurs not infrequently. To change the eponym 'Peyronie's disease', however, seems unjustified. It is an homage to François Gigot de la Peyronie (1678-1747) surgeon to King Louis XV and founder of the French Académie de Chirurgie.
Narrowed and rudimentary portal vein branches were observed in the livers of specified-pathogen-free rats which, at the age of 6-11 weeks, showed poor condition and reatrded growth. At autopsy abdominal venous distension and congestion suggestive of portal hypertension and collateral circulation appeared to have developed. The cause of the observations and their significance in view of the use of the rats are unknown.
A detailed case history and macroscopical description is given of a destructive tumour of the lower jaw, treated by the Utecht prosector Petrus Koning in the years 1811-1813. The macerated skull demonstrating the enormous cystic tumour is still preserved in the Pathological Institute of the State University, Utrecht, and shows unmistakable ameloblastoma. This case is one of the first-if not thĕ first-proven cases of ameloblastoma recorded in history. Some remarks on the conservative treatment which was used, the incidence of ameloblastoma in history and its nomenclature are included in this article.
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