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G T Reizner

Publications and source records attributed to G T Reizner.

24 records · Page 2Linked to original sources
PubMed1988

Diffuse dermal neutrophilia in urticaria.

Twenty-three cases of diffuse dermal neutrophilia and urticaria were reviewed. Evidence of vasculitis or other disease was not present. Direct immunofluorescence was done in 19 cases and was positive but nonspecific in 14. The presence of angioedema (10 cases), dermographism (2 cases), atopy (4 cases), drug reactions (6 cases), and infections (6 cases) was similar to that seen in cases of urticaria without diffuse dermal neutrophilia. Nearly 9% of the cases of urticaria show this histologic pattern, and when cases of neutrophilic urticaria are added, 15.8% of cases of urticaria were found to show a major neutrophil component in the inflammation. In urticaria, neutrophilia may be part of an intense stimulus response pattern.

Angioedema↗
PubMed1988

Bowen's disease and internal malignancy. A matched case-control study.

Bowen's disease has been reported as a skin marker for internal malignancy. We conducted a matched case-control study to evaluate the significance of this link. Fifty white men with Bowen's disease diagnosed between 1977 and 1986 at a Veterans Administration Hospital were selected for study. These patients were matched by age, sex, race, and date of skin biopsy to 50 patients with basal cell carcinoma (control group 1) and another 50 patients with other dermatoses (control group 2). The original 50 patients with Bowen's disease include 12 (24%) with various internal malignancies. In comparison, nine patients (18%) in control group 1 and seven patients (14%) in control group 2 had internal malignancies. These numbers do not substantiate a statistically significant increase in the frequency of internal malignancies in Bowen's disease. We therefore conclude that Bowen's disease is not a skin marker for internal malignancy in elderly white men.

Adult↗
PubMed1988

Necrobiosis lipoidica diabeticorum with cholesterol clefts in the differential diagnosis of necrobiotic xanthogranuloma.

The histopathologic findings in 331 cases of necrobiosis lipoidica diabeticorum seen during a 50-year period were reviewed. Three cases showing cholesterol cleft formation were found. All 3 cases were associated with severe diabetes mellitus. The differential diagnosis of importance is necrobiotic xanthogranuloma. Common features included extensive hyaline necrobiosis and foreign-body giant cells. Atypical and Touton-type giant cells are more common in necrobiotic xanthogranuloma. Vascular changes in necrobiotic xanthogranuloma may include granulomatous involvement of muscular walls with thrombosis. Explanations for cholesterol cleft formation are offered. When cholesterol clefts are seen in biopsy specimens of necrobiosis, necrobiotic xanthogranuloma must be ruled out. In addition, when found in necrobiosis lipoidica diabeticorum, these clefts may imply diabetes mellitus with complications.

Adult↗
PubMed1987

Nonmelanoma skin cancer in Japanese residents of Kauai, Hawaii.

A prospective 3-year survey of nonmelanoma skin cancer in Japanese-American residents of the Hawaiian island of Kauai was conducted beginning in January 1983. The crude rate for basal cell and squamous cell carcinoma was 123/100,000, 88 times higher than the corresponding figure from Japan. This discrepancy may be attributed to an increase in ultraviolet exposure due to lifestyle and latitude, but arsenic exposure may also have played a role. Nonmelanoma skin cancer in Japanese in Hawaii appears to be a significant problem that has not been appreciated because these malignancies are not reportable to tumor registries.

Aged↗
PubMedDate not supplied

Bowen's disease (squamous cell carcinoma in situ) as a skin marker for internal malignancy: a case-control study.

Bowen's disease has been viewed as a skin marker for internal malignancy by dermatologists for decades. If substantiated, it certainly would help in early detection of an occult malignancy. We conducted a matched case-control study to evaluate the significance of this link. Ninety patients with Bowen's disease diagnosed between 1972 and 1986 were selected for study. These patients were matched by age, sex, race, and date of biopsy for diagnosis (or treatment) to 90 other patients chosen as controls. Six patients in the Bowen's disease group and three patients in the control group had internal malignancy during the period after the date of biopsy or treatment (P greater than 0.4). The present study cannot substantiate the claim that Bowen's disease is a skin marker for internal malignancy.

Adult↗