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Biomedical subjects

G Törnqvist

Publications and source records attributed to G Törnqvist.

11 recordsLinked to original sources

Trabeculectomies. A long-term study.

This study comprises 277 primary open-angle glaucomas in 239 patients followed up to 10 years after trabeculectomy. Sixty-four per cent had capsular glaucoma and 36% simple glaucoma. The number of cases showing no progression of glaucoma damage and not needing additional medical therapy decreased slowly with time. Seventy-five per cent showed no progress after one year, 70% after 2 years, 57% after 5 years and 42% after 10 years. There was a significant trend that fewer capsular glaucomas progressed than simple glaucomas. High pressure levels before trabeculectomy did not indicate a bad prognosis. Cases with advanced or moderate glaucomatous damage seemed to have the same prognosis. Cataract was a common complication; a 50% reduction of preoperative visual acuity was found in 37% of eyes after 5 years of follow-up.

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Cytogenetical observations in nine ocular malignant melanomas.

The cytogenetical findings in one conjunctival and eight uveal melanomas are reported. Six of the intraocular tumors displayed clonal abnormalities. In two of these cases there were both extensive numerical and structural aberrations. Only the single ciliary body melanoma showed the deviations monosomy 3 and gain of 8q considered typical of uveal melanomas. No preferential pattern could be discerned for the clonal abnormalities in the other uveal melanomas. The one conjunctival tumor, arising in an area of precancerous melanosis, showed only a small clone with a 4q+marker. The clonal abnormalities in the nine cases showed no similarities to those on record for cutaneous melanomas.

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