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Biomedical subjects

G Takács

Publications and source records attributed to G Takács.

At least 19 recordsLinked to original sources

Obstetric anaesthesia in Hungary.

A nation-wide survey of pain relief in childbirth in Hungary was carried out in 1993. Information was provided on 104 137 deliveries in 98 units. The frequencies of different methods of pain relief for vaginal delivery were as follows: systemic opiates in 7387 cases (8.3%), epidural analgesia in 4611 cases (5.2%) and inhalational analgesia (nitrous oxide) in 4470 cases (5%). Epidural analgesia was available in 36 units (36.7%). For 71 744 vaginal deliveries (80.5%) no pain relief was provided at all. For caesarean section (n = 13240) the rate of spinal or epidural anaesthesia was 36.7%. It was concluded that despite an increasing rate of pain relief in labour elsewhere, the numbers of epidurals are still rather low in Hungary.

Journal Article↗

[Gynecologic and obstetric anesthesia in Hungary 1993].

Authors publish findings of a nationwide survey of pain relief in childbirth in Hungary carried out during the year of 1993. Informations were provided on 104,137 deliveries in 98 units. At 71,744 vaginal deliveries (81%) not any types of pain relief were used. The frequency ot different types of pain reliefs at vaginal deliveries were as follows: systemic opioids at 7387 cases (8.3%), epidural analgesia at 4611 cases (5.2%) and inhalational analgesia (nitrous oxide) at 4470 cases (5.0%). The availability of epidural analgesia at 62 units was absent. The rate of spinal--epidural analgesia at Cesarean sections was 37% (n = 13,240). At gynaecological laparotomies (n = 18,219) the rate of general anaesthesia was 98%, this rate at vaginal hysterectomies was 56.8% (n = 1568). Authors conclude that the rate of pain relief in labour in Hungary is unreasonably low. The reason of it is the lack of anaesthetists and also the traditional view, which does not recognize the importance of the pain relief in labour.

Adult↗

[Preoperative and surgical protocols for better implant integration].

In implant placement, different bone densities require different implant types in order to achieve maximum stability. Therefore, careful preoperative planning is essential to diagnose and/or augment the bone, to select the correct size and type of implant for each individual case, and to establish the appropriate surgical protocol. This paper and presentation discuss the essentials for establishing such protocol, ie, the quality and quantity of bone, type and size of implants, surgery, progressive loading, and shifting of the mastication forces. Serious errors in planning first appear as short-term failures, and they indicate inadequacy in osseointegration in the healing phase or overloading caused by the superstructure. Less grave errors occur later as long-term failures, due to the width, depth, and density of the bone and the angulation of the implant. Appropriate components have to be used for different types of bone: Uncoated screws are the best solution for D1 and D2 types of bone; coated screws should be used in the presinus area and after nerve transpositioning. Cylindrical implants are best suited for subantral augmentation, using a narrow drill; the bone bed is progressively widened by a conic osteotome, and the technique provides a good stability. Free gingival transplant is indicated in cases with insufficient keratinized gingiva. Masticatory overloading can be avoided by reducing the occlusal table, decreasing cusp inclination, and anteriorizing the upper mastication areas.

Bone Density↗

[Use of hydroxyapatite (Ceros-80) in dental implantology].

The use of lyodura prevents the loss of hydroxyapatite crystals from the operated area during the healing period. Its protective membrane effect prevents infection and other problems during healing. Histological studies have shown that the combined use of "Ceros 80" hydroxyapatite and lyodura within 20 months resulted in the development of new, osseointegrated considerable amount of bone. This bone-hydroxyapatite bond is the base for further implantological and prosthodontic procedures.

Adult↗

Use of Klion suspension in paediatry and gynaecology.

Klion suspension was given to 42 girl and woman patients suffering from vaginal trichomoniasis. Negativity for Trichomonas was recorded in 73.8% of the cases in response to the first 10-day cure, and in 90.5% of the patients following repeated cures. The therapy had no notable side-effects. The liquid form of the medicine proved to be advantageous especially in the treatment of young girls but the possibility to take the drug diluted in soft drinks also facilitated the treatment of the partner.

Administration, Oral↗

Surgical muscle relaxation with Norcuron injection.

Norcuron, a new, non-depolarizing muscle relaxant has been used for anaesthesia of 48 obstetrical and gynaecological operations. The product could assure the required neuromuscular blockade in all discussed operation types when given either in single or repeated doses. It's action developed rapidly and, if required, it could be antagonized within a short period. The drug had no unfavourable circulation influencing side-effect and could be combined with the used anaesthetics. In newborns delivered by Caesarean section pathological changes were observed nor in Apgar scores, neither in the cardiorespiratory adaptation.

Adult↗

Use of triphasic Tri-Regol tablet in women of borderline age.

Tri-Regol, a triphasic oral contraceptive tablet, has been used by 52 young and premenopausal fertile women during 189 cycles. Pregnancy was not observed, complication did not occur, none of the women discontinued the treatment because of health reasons. The women of both borderline age groups tolerated the tablet well which even exerted a therapeutic effect by controlling partly puberal cycle anomalies, partly premenopausal complaints. According to the author's opinion Tri-Regol is a valuable contraceptive for borderline age groups and may be useful as hormone therapy in certain cases.

Adolescent↗

Usefulness of acid and gastric juice secretion decreasing action of cimetidine in anaesthesia for the prevention of aspiration.

The effect of Histodil injection on the amount and pH of the gastric juice has been examined in women undergoing caesarean section under intratracheal anaesthesis. According to the results cimetidine decreases the volume and acidity of gastric secretion to a significantly higher extent than the pretreatment with atropine as a single agent. Maximum effect may be expected within 60-90 minutes. With Cimetidine pretreatment the risk of aspiration and pneumonitis may be prevented.

Adult↗

Contribution to the methodology of optimization and in-process control of some physical properties of pharmaceutical bulk substances and granulates.

Many experts consider drug analysis exclusively as a chemical measuring technique. In the pharmaceutical industry, physical and physico-chemical parameters form an integrated part of the quality specification, because they play an essential role both in quality assurance and in the technical and economic aspects of production on the commercial scale. Such physical and physico-chemical properties are analysed by special, non-chemical methods. In their programme of systematic research in this field, the authors have elaborated new methods to test some essential properties of powders and granulates used in the production of compressed tablets. The following test and production methods have been developed: (i) the determination of flowing-sliding characteristics of granulates based on the measurement of the mass-flow (g s(-1)) and mass-flow density (g s(-1) cm(-2)); (ii) the determination of optimum granulometric parameters with regard to tablet diameter; (iii) the direct determination of the temperature-dependent equilibrium vapour pressure; and (iv) the compression of tablets under controlled temperature.

Journal Article↗