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Biomedical subjects

G Tassoni

Publications and source records attributed to G Tassoni.

46 records · Page 3Linked to original sources

Aversive conditioning of homozygous and heterozygous D.I. Brattleboro rats in the light-dark box.

Active and passive avoidance, and conditioned freezing acquisition and retention were studied in HODI and HEDI Brattleboro rats. All animals were from the same source and of the same age and sex. The light-dark box test was employed. 0.6 and 2.0 mA footshocks were administered for the same number (7) of daily trials. Extinction time-course was followed for seven consecutive daily trials. Passive avoidance: the conditioned response was acquired and retained equally well by all Ss and for both shock intensities. Active avoidance: for 0.6 mA shocks HODI Ss acquired and retained the response significantly better than HEDI Ss; for 2.0 mA shocks the response was acquired equally by both groups of Ss, and retained significantly better by HODI Ss. Freezing: in general, HODI Ss exhibited less freezing then HEDI Ss. The diverse conditioned behavior of HODI and HEDI Ss in this paradigm, which allows the contemporaneous investigation of several aversive responses, does not support the hypothesis that vasopressin deficiency impairs learning and memory in the rat.

Animals↗

Early experience with Telehealth during sport activities.

In order to verify the usefulness of a system designed to provide participants of sport competitions with a cardiological emergency service, the authors utilized a cardiotelephone apparatus during a "24-hour Marathon race" in which 1008 subjects took part. In 18 cases, an ECG was transmitted owing to various symptoms after exertion. One case of pseudoischaemia and one of complete A-V block were registered. The authors emphasize the importance of a telephone ECG transmission system as a special aid able to cut down the intervention time without moving the patients.

Adolescent↗

Spontaneous and conditioned behavior of Wistar and Long Evans rats.

Spontaneous behavior (locomotion, feeding, drinking, and exploration in a two box apparatus) as well as conditioned behavior (passive and active avoidance responding, and freezing in the light-dark box apparatus) were studied in naive male Wistar and Long Evans rats. Concerning spontaneous behavior, Long Evans rats were more active during both light and dark periods, and showed better exploratory performance than Wistar rats. Concerning conditioned behavior, Long Evans rats acquired and retained better active and passive avoidance responses, and exhibited longer initial freezing than Wistar rats in the range of 0.6-1.4 mA footshocks. The results better define the important behavioral differences existing between the two strains, Long Evans rats showing consistently a higher level of alertness and a better conditioned performance.

Animals↗

Conditioned freezing (generalized motor inhibition) in several rat strains: its usefulness in assessing somato-vegetative responses to nociceptive stress.

Conditioned initial freezing duration was timed in the light-dark box test. Four genetically diverse groups of rats (Wistar, Long Evans, Brattleboro heterozigous for diabetes insipidus, Brattleboro homozygous for diabetes insipidus) were employed. 0.6 mA and 1.8 mA footshocks were administered as nociceptive stressors. The results showed that freezing duration easily and conveniently measures the animal's capacity of responding to stress. This finding is discussed in terms of genetically determined hormonal make-up and of CNS receptorial mechanisms. Initial freezing duration is proposed as a tool to evaluate stress responses.

Animals↗