Biomedical subjects
Publications and source records attributed to G Theander.
Observations made in 455 Malmö infants with assumedly normal ossification of the femoral heads were used for establishing reference standards for the age at onset of the ossification and for the size of the ossification centers according to sex and age.
A review of the films obtained in 124 infants conservatively treated for congenital dislocation of the hip revealed deviations from ordinary development of the femoral head before as well as after the treatment. Analysis of these deviations suggested initial acceleration of ossification, modified by retardation ipsilateral to dislocation and followed by bilateral deceleration of growth after treatment.
In 10 children with altogether 17 malformed thumbs radiography revealed true triphalangism in 13 of the thumbs and pseudotriphalangism in the remaining 4. Two varieties of triphalangism were distinguished, and clinically significant morphologic variation was recognized also in pseudotriphalangism.
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A case of the Larsen syndrome is reported in which postmortem examination of the brain revealed glial proliferation resembling tuberous sclerosis. The differential diagnosis of the syndrome and the possible significance of the lesions are discussed.
Retention of contrast medium in the renal pelvis for several days after urography is illustrated in 2 cases of obstructing urinary stones. In a third case water-soluble contrast medium was used for retrograde pyelography before nephrectomy and was retained in the stenotic ipsilateral ureter 7 1/2 months after the operation. A further case exemplifies retention in the seminal vesicles 2 months after vasoseminal vesiculography.
Mucosal folds in the ureter or renal pelvis were demonstrated in 2 children and 27 adults with urolithiasis. It appeared from the sequence of events observed in these cases that the folds occurred in a redundant mucosa following an episode of mural stretching. Urinalysis, including bacterial culture in the majority of cases, showed infection in only 3 of the adults.
A retrospective inspection of films from colon examinations revealed evidence of lymphoid hyperplasia in 24 of 229 infants and children. The condition is more frequently demonstrated at double contrast examination than with the conventional barium enema. Analysis of symptoms and signs and information obtained at follow-up suggests that this condition is usually, if not always, benign in childhood.
Two cases of intraspinal abnormalities combined with a characteristic unilateral protuberance of the iliac bone are reported. A search of the literature revealed only 2 other examples of this condition, but analysis of the associated findings in all 4 cases suggested a specific syndrome consisting of the iliac protuberance, other ipsilateral osseous abnormalities, and occult spinal dysaphism including intraspinal lipoma.
A review of the radiographs obtained at 200 unselected micturition urethrocystographies in boys revealed orificial insufficiency of prostatic ducts (OIPD) in 29. Urinary infection had been demonstrated in 131 these cases including all of the boys with OIPD except one, who had neurogenic dysfunction of the urinary bladder. --In one boy OIPD was discovered at the age of 7 weeks following treatment first for neonatal sepsis and then for urinary infection, both caused by the same phage type of Staphylococcus aureus. Bacteriologic examination of the blood and urine had suggested recovery, but further investigated disclosed survival of the bacteria in the prostate.
48 boys examined with urethrocystography on all together 129 occasions and shown to have orificial insufficiency of prostatic ducts were studied for associated for associated abnormalities. In 44 cases the insufficiency could be attributed to urinary infection complicating urethral obstruction or neurogenic dysfunction of the urinary bladder or to any one of these three abnormalities alone. The age at which the insufficiency occurred, the time it persisted, and the extent to which it involved the prostate were also studied.
Clinodactyly in 10 fingers (9 patients) with longitudinally bracketed diaphysis (LBD) was treated surgically with various methods. In 4 cases with LBD in the middle phalanx of a triphalangeal thumb this phalanx was removed and the ligaments reconstructed. In the other 6 digits the LBD was in the base phalanx of a thumb or in the middle phalanx of some other digit. One of these was treated in infancy with transverse resection of the bracket. In 3 cases (4 digits) wedge osteotomy with reversal of the wedge was carried out. In the remaining case simple osteotomy was performed and a wedge-shaped bonegraft was interposed in the space created. Treatment in the last-mentioned case was unsuccessful because postoperatively the graft slipped out of position, but in all other cases the results achieved appear satisfactory.
A bizarre and apparently hiherto unknown malformation complex mainly affecting the upper limbs was observed in a boy who underwent radiologic examination at 6 and 15 years of age. The most conspicuous abnormalities are represented by knee-like elbows and carpal elements resembling tarsals, additionally there was also marked overgrowth of the tarsal bones. The combination of these virtually unique malformations might suggest the existence of some early morphogenetic factor responsible for differentiation of the lower limbs and capable create ectopic elements of the lower limbs by conversion of the homologous parts of the upper limbs.