Biomedical subjects
Publications and source records attributed to G Thess.
A report is given on a 39-year-old man, who developed, after a tick bite, erythema, progressing symptoms and, after 3 years, showed the typical clinical and echocardiographic signs of a dilative cardiomyopathy. A serological test for Lyme Borreliosis was positive. Most of the symptoms disappeared after high-dose penicillin therapy.
It is reported on a case of lyme-borreliosis with cardiac participation. Here the case in question were disturbances of the transmission of impulses in form of a third-degree atrioventricular block, which temporarily underwent a cardiac pacemaker treatment. By means of the antibiotic treatment recommended in the literature a restitutio ad integrum was achieved.
All the 18 patients with acrodermatitis chronica atrophicans (ACA) showed the specific borrelia antibody at the indirect immunofluorescence assay. The patients exhibited a large spectrum of arthritic and neurologic complaints besides the typical cutaneous symptoms. Changes of proteins, of liver-typical parameters and of the electrocardiogram are also assigned to the Lyme-borreliosis. The penicillin therapy - three times accompanied by a Jarisch-Herxheimer-reaction - led to regression of the clinical changes. The secessions of borrelia-antibody-titers happens only very delayed. That is why it can not be used for the direct therapy control. The increased documented polysymptomatic of Lyme-borreliosis requires a wider knowledge and the country-wide possibility of specific diagnostic.
Chlamydia trachomatis is said to play an important role in the pathogenesis of gynecologic, perinatal and neonatal infectious morbidity. Chlamydia trachomatis is responsible for several infectious syndromes in non-pregnant women, mothers and their offspring. We investigated the incidence of Chlamydia trachomatis in 353 non-pregnant and pregnant women without complaints and in 50 newborn. Chlamydia trachomatis was isolated from 6% of genital carcinoma, about 20% of different gynecological diseases and pregnant women within the first and third trimenon, 35% of puerperas and 10% of newborns. The prevalence of Chlamydia trachomatis antibody occurred in 34 to 55% of the non-pregnant and pregnant women and in 38% of the newborns. We propose a screening for Chlamydia trachomatis infection in high-risk patients and in pregnancy and a treatment of infected individuals.
Dark-field microscopy, fuchsin stain and Fontana silver stain were used for a rapid detection of spirochaetes in fresh materials from patients with Lyme-borreliosis. The spirochaetes were shown to be present in 2 cerebrospinal fluids, 2 synovial fluids and in one brain cyst fluid. It is pointed out that these techniques require further improvement and optimization.
Explore the source record for details and available documents.
Eight cases of Lyme borreliosis of clinical certainty with carditis are reported. In six patients, AV-blocks were predominant, two patients had a myopericarditis. Six acute cases were seropositive, but one case remained seronegative. The titer was border-line in that patient, who was studied 4 years after the acute disease. A Lyme carditis should be considered in each case, in which AV-blocks appear acutely.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.