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Biomedical subjects

G Thiede

Publications and source records attributed to G Thiede.

14 recordsLinked to original sources

[CT diagnosis of glomus-jugulare tumours].

Glomus-jugulare tumours (chemodectomas, non-chromaffin paragangliomas) are semi-malignant tumours arising from the glomus structures of the jugular bulb. They are soft tissue tumours which usually expand the jugular foramen and destroy its bony margins. Conventional methods of examination are therefore very effective. However, they only demonstrate the bone destruction and are therefore an indirect method for showing the tumour. The actual size and extent of the tumour, which are important for the surgeon or radiotherapist, cannot be demonstrated by simple x-rays. Computer tomography is very effective in the diagnosis of soft tissue lesions in the skull. CT is therefore of great importance in the diagnosis of glomus-jugulare tumours.

Female

[Fibrous dysplasia of the skull--a radiological, computer tomographic and scintigraphic study (author's transl)].

The diagnosis of fibrous dysplasia (Jaffé-Lichtenstein) of the skull can generally be made by plain films, occasionally supplemented by tomography. The differential diagnosis from sclerosing meningiomas in the anterior fossa can usually be made by cranial computer tomography. Cerebral scintigraphy does not play an important part in the differentiation from a meningioma. Total body scintigraphy, on the other hand, is useful, particularly in distinguishing between monostotic and polyostotic bone conditions. Invasive neurological methods, such as cerebral angiography, are in our opinion unnecessary unless there are definite clinical focal cerebral symptoms in the presence of a normal computer tomogram.

Diagnosis, Differential

[Estimation of individual renal function by Tc-DMSA-uptake (author's transl)].

Hg-Cl2-accumulation and early hippuran uptake are widely used for the estimation of individual renal function, a clinically important procedure in nephrological-urological nuclear medicine. After clinical experience in more than 2500 patients we investigated the assessment of individual renal function by the uptake of Tc-DMSA, a new radiopharmaceutical for renal scintigraphy. Tc-DMSA-uptake was measured after application of 0.8-1.6 mCi Tc-99m-DMSA by a scintillation camera connected to a computer system and by a rectilinear scanner with data storage, additionally hippuran kinetics were registered with a scintillation camera, the total body clearance was performed due to the method of Oberhausen with a modified whole body counter. A good agreement and high correlation between Tc-DMSA-uptake with background corection and the unilateral renal clearance could be established. This easily available and clinically valuable method also can be adjusted to institutions with a rather simple equipment.

Evaluation Studies as Topic

[Hemihypertrophy, nevus sebaceous, multiple bone cysts and cerebroretinal angiomatosis: a complex phakomatosis].

Report on a girl, who died at the age of 6 1/2 years having exhibited different dysplasias which are characteristic features of several phakomatoses: congenital cutaneous pigmentations, fibrolipoma of the scalp, hypertrophy of the right leg, multiple cysts of the long bones (fibrous dysplasia), and an aneurysma racemosum of the retina and mid-brain (syndrome of Bonnet-Blanc-Dechaume).

Angiomatosis

[Malignant synovialoma (author's transl)].

Based upon 351 cases of malignant synovialoma from the literature and 12 own observations clinical and roentgenographic findings, differential diagnosis, therapy, and prognosis are discussed. Because of early recurrencies and metastases early diagnosis is most important for therapeutic results. By means of radical surgery and subsequent intensive irradiation of the previous tumor site and the draining lymphatics a 5-years survival rate of 30-50% can be achieved.

Age Factors