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G Tognini

Publications and source records attributed to G Tognini.

23 records · Page 2Linked to original sources
PubMedDate not supplied

Non-Hodgkin lymphomas of the ovaries: MR findings.

PURPOSE: The goal of this work was to describe MR findings (morphology, structure, signal intensity) of ovarian non-Hodgkin lymphoma (NHL). METHOD: We reviewed the MR images of five female patients aged 13-70 years (mean 46 years) with histologically proven NHL of the ovaries. We evaluated morphological and signal intensity findings of the lesions. MR features were correlated with pathologic parameters. RESULTS: All the patients were affected by B-cell NHL; one patient showed a primary involvement of the ovaries; in one patient, ovarian disease was diagnosed 30 months after surgical resection of a primary uterine lymphoma; the remaining three had a systemic lymphoma. In three cases, the ovarian involvement was bilateral. The mean size of the lesions was 7.9 cm. All the lesions showed homogeneous low signal intensity on T1-weighted images and intermediate to high intensity on T2-weighted images. The postgadolinium images showed mild to moderate heterogeneous enhancement. The peripheral enhancement was better demonstrated in fat-suppressed images. CONCLUSION: The diagnosis of primary ovarian lymphoma should be considered in the presence of large bilateral solid ovarian masses with homogeneous appearance (low signal on T1 and mildly high on T2) without infiltrative pattern of growth or regressive changes (necrosis, hemorrhage, calcifications) and with little contrast enhancement.

Adolescent↗
PubMedDate not supplied

Lipomatous tumors of the stomach: CT findings and differential diagnosis.

This article reviews the computed tomography imaging features of a variety of gastric tumors containing fatty tissue. Lipoma, angiolipoma, liposarcoma, and teratoma are described. Differential diagnosis includes primary and reactive lipomatosis, carcinoma engulfing the perivisceral fat thus mimicking differentiated liposarcoma, and mesenchymal gastric and peritoneal neoplasms.

Adult↗
PubMedDate not supplied

[Gastric stromal tumors. Findings with computerized tomography].

PURPOSE: Gastric stromal tumors are an ill-defined group of lesions arising from muscle wall cells and characterized by extremely variable biological patterns. Thanks to modern immunohistochemical and ultrastructural techniques, four main classes of these lesions have been identified, namely: 1) tumors with differentiation toward smooth muscle cells; 2) tumors with differentiation toward neural elements; 3) tumors with dual differentiation toward both cell types; 4) tumors lacking differentiation toward either cell type. We investigated the yield of CT in diagnosing and characterizing gastric stromal tumors. MATERIAL AND METHODS: We retrospectively reviewed the CT findings of 38 patients (15 men and 23 women; mean age 51 years) with pathologically proven gastric stromal tumors, namely 31 of myoid origin, 4 of neural origin, 2 with both muscle and neural differentiation, 1 lacking differentiation with either cell type. Morphological (size, margins, growth pattern, enlarged lymph nodes, metastases) and structural (density, calcifications, necrosis, cystic changes, enhancement patterns) parameters were evaluated and compared with histopathologic diagnosis. RESULTS: The myoid tumors involved gastric fundus in 9/13 and 5/7 benign lesions and lesions with variable biological patterns, respectively, while the malignant tumors exhibited diffuse involvement in 7/11 of cases. Eleven of 13 benign lesions had regular shape and a diameter +/- 5 cm, while 5/7 intermediate tumors and 7/11 malignant ones were 6-10 cm and over 10 cm (1/7 and 3/11, respectively). Tumor growth was intramural (6/13) or mixed (5/13) in the benign lesions, mainly exophytic in the malignant ones, and finally variable (2/7 intramural, 3/7 exophytic and 2/7 mixed) in the tumors with intermediate patterns. Calcifications were identified only in 3 benign lesions. Structure was homogeneous in 11/13 of the benign lesions with regular contrast enhancement (10/12), heterogeneous due to necrotic areas in nearly all (10/11) or most (5/7) malignant and intermediate forms, respectively. Enlarged lymph nodes (4/11) or synchronous metastases (7/11) were found in the malignant lesions. Our two schwannomas had a pseudocystic structure with regular peripheral contrast enhancement; the neurofibroma was characterized by multiple, markedly hypodense and hypovascular lesions. Both the malignant neurogen form and the two tumors with dual differentiation showed a diffuse, aspecific and infiltrating pattern. The lesion without differentiation had a "benign" shape and structure even though it developed metastases two years after radical surgery. CONCLUSIONS: Despite the lack of specificity of CT patterns of gastric stromal tumors, these parameters are useful in differentiating benign from overtly malignant forms. The definition "gastric stromal tumor with benign, variable, or malignant macroscopic appearance" should be used in the radiologic report.

Adult↗