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Biomedical subjects

G Tringali

Publications and source records attributed to G Tringali.

7 recordsLinked to original sources

[Clinical study of the efficacy of and tolerance to nimesulide in suppository formulation in pain-inflammatory pathologies of the ear, nose, and throat].

The efficacy and tolerability of a new pharmaceutical form of the non-steroid anti-inflammatory drug. Nimesulide have been studied in a double blind study compared with flurbiprofen, in 98 patients aged between 18 and 75 suffering from pain-inflammatory pathologies of ENT nature. Both drugs, administered in a dose of one suppository twice a day for 7 days, showed marked anti-inflammatory, analgesic and antipyretic activity and produced a significant, progressive improvement in the typical symptoms of the inflammatory state up to their complete remission. Nimesulide evidenced greater speed and duration of therapeutic action. Assessment on the effectiveness and tolerability as expressed separately by the physician and patient were positive in almost all cases of both treatments.

Adult

[Electroimmunodiffusion reaction in the diagnosis of syphilis (author's transl)].

A group of 800 human sera, obtained from syphilitic and nonsyphilitic individuals were tested in the counterimmunoelectrophoresis (CIE) technique with Reiter protein antigen. The sera were assayed for comparison in the following treponemal and nontreponemal tests: standard serologic tests for syphilis with cardiolipin; complement fixation (Kolmer 1/5 vol) with Reiter protein antigen (RPCF); T. pallidium immobilization (TPI) test; haemoagglutination test for T. pallidum antibodies (TPHA). The sensitivity and specificity of CIE test, its simplicity, the low cost, the possibility of practical application as a routine test for syphilis serology were discussed.

Antibodies

[The passive hemagglutination test in the diagnosis of syphilis].

Studies were carried out on the comparative value of passive haemaglutination, cardiolipin and treponema tests in a total number of 4327 sera syphilitic patients in various stages of the disease and apparently normal subjects or free of syphilis. The results demonstrated the specificity and sensitivity of passive haemagglutination in all the stages of syphilis. In view of the qualities and simplicity of the test, the author recommends it as a screening test combined with a micromethod using the cardiolipin antigen (flocculation test).

Complement Fixation Tests

[Isolation of menincococci in Palermo during a course of seasonable recrudescence].

Three strains of Neisseria meningitidis were isolated from young patients during an outbreak of cerebrospinal fever in Palermo, fourteen from their family contacts. All strains from patients and ten of the strains from contacts fell into group C, two of the others into group B; two were untypable strains. All the strains belonging to group C exhibited sensitivity to sulphonamides and to other antibiotics tested. Strains of group B appeared resistant to sulphonamides and to combined trimethoprim-sulphamethoxazole; they were also slightly resistant to streptomycin and tetracyclines.

Disease Outbreaks

[Antibody response in subjects with meningococal disease and in healthy carriers of Neisseria meningitidis].

Antibodies against Neisseria meningitidis in sera of childrens suffering from cerebrospinal fever and in sera of their family contacts were assayed by serum bactericidal test, indirect immunofluorescence and passive hemagglutination. Changes in antibody titers were showed in the course of the observations in many patients but only in few contacts. The immune response during meningococcal disease and the sensitivity of different serological methods were discussed.

Antibodies, Bacterial