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Biomedical subjects

G U Detlefsen

Publications and source records attributed to G U Detlefsen.

12 recordsLinked to original sources

[Treatment of episiotomy wound infections. Incision and drainage versus incision, curettage and sutures under antibiotic cover--a randomized trial].

Conventional, "open" treatment of episiotomy wound infections was compared to incision, curettage and primary suture under antibiotic cover in a prospective, randomized study. During the period 1.5.1986-31.12.1988 there were 4154 vaginal deliveries with episiotomy, of which 20 (0.48%) became infected. Seventeen of these patients consented to enter the study. Median time for healing was 12 days following suture and 19 days after "open" treatment (not significant). Hospitalization time was the same in the two groups. No re-infections were seen. A need for vaginal plastic repair was found in three of nine of the conventionally treated patients and in none of the patients in the suture group (not significant). It is concluded that treatment of episiotomy wound infections with incision, curettage and primary suture under antibiotic cover is an attractive, safe ad convenient alternative treatment.

Adult↗

Treatment of Bartholin's abscess. Marsupialization versus incision, curettage and suture under antibiotic cover. A randomized study with 6 months' follow-up.

Conventional marsupialization was compared with incision plus curettage and primary suture of the abscess cavity under antibiotic (Clindamycin) cover in a prospective, randomized study of 32 patients with Bartholin's abscess. The median time to healing was 5 days less after suture than after marsupialization alone. The difference was statistically significant. 29 patients were followed up for 6 months. Recurrence of abscesses tended not to be more frequent after suture, making suture an attractive, safe and convenient alternative treatment for Bartholin's abscess.

Abscess↗

Immature ovarian teratoma in a postmenopausal woman.

We report the first case of immature ovarian teratoma occurring after menopause in a 57-year-old, 3 years postmenopausal woman. Within one year after resection of the teratoma she developed peritoneal botryoid rhabdomyosarcoma, which probably originated from initially unrecognized rhabdomyoblasts in the teratoma. The patient died 6 months later from progressive disease after a transient adriamycin-induced tumor response. The literature on ovarian immature teratoma and ovarian rhabdomyosarcoma is briefly reviewed, and the available treatment is discussed.

Cyclophosphamide↗

Complete staining of human spermatozoa and immature germ cells combined with phase contrast microscopy.

A method combining Janus green B and Thymol blue stains the anterior part of the head, the nuclear membrane, middle piece, and tail of spermatozoa light green and the nucleus deep purple. The method provides excellent stained preparations for the evaluation of sperm morphology by phase contrast microscopy. It produces significantly less abnormal spermatozoa compared with the Papanicolaou stain.

Azo Compounds↗