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Biomedical subjects

G Uzunov

Publications and source records attributed to G Uzunov.

13 recordsLinked to original sources

[The early bicycle ergometry test in drug-stabilized patients with unstable angina pectoris--the correlation with coronary angiography].

The relation between the results of the early submaximal symptom-limited bicycle ergometry [correction of veloergometric] test and coronary angiography were examined in 127 patients with unstable angina pectoris stabilized by medicaments. In 19 (15.0%) patients the test was negative and in 108 (85%) patients the test was positive (angina pectoris and/or ST depression greater than or equal to 0.1 mV at 80 ms after the point J of the ECG). Between the results of the early bicycle ergometry [correction of veloergometric] test and the coronary angiography, performed soon after the test, there was a close correlation. By using strict criteria or a combination of criteria for assessment of residual ischemia the test can with great accuracy differentiate the patients with multivascular from those with monovascular disease or with healthy coronary vessels.

Adult↗

[Prevention of ruminal acidosis during the intensive fattening of weanling lambs].

Forty-eight intensely fattened weaned lambs, divided into 2 groups were used to test the prophylactic effect of lasalocid with regard to rumen acidosis. The animals were offered complete mixtures ad libitum, containing 80 per cent concentrates and 20 per cent cut meadow hay. The weaned lambs of the test group were given the preparation "Avatek' (with 15 per cent lasalocid) in the course of 60 days with the feed at the rate of 250 g per ton of the complete mixture. Periodic biochemical and hematologic investigations on the animals of the two groups were carried out, following up their body development. The animals of the test group showed higher level of alkaline reserves, volatile fatty acids, and pH values of the rumen content and lower level of lactic acid in the blood and rumen liquid. By the 45th day of the experiment certain changes in the biochemical indices took place (rise of lactic acid and drop of alkaline reserves) as well as arrest of the weight development in the test animals. The average daily gain of the test group over the entire experimental period was 7.74 per cent higher than that of the control animals.

Acidosis↗

[Effect of pyrogenes on the activity and isoenzyne spectrum of lactate dehydrogenase in tissues and blood serum of guinea pigs].

It is established that 2,4 DNP effect produces no changes in the total activity of lactate dehydrogenase (LDH, EC 1.1.2.3) in the heart, liver and blood serum of guinea pigs. Under the effect of lipopolysaccharide obyained from Bact. alkaligenes faecalis it increases in the liver and heart. A change in the isoenzymic spectrum is characterized bt a decrease in the LDA3, LDH4, LDH5 activity in the blood serum, an increase in the activity LDH1, LDH2 and a decrease in the LDH4, LDH5 in the myocardium, disappearance of LDH, in the liver under the effect of bacterial lipopolysaccharide. Under the effect of 2.4 DNP the activity of LDH3 in the liver increases and that of LDH3 DECREASES.

Animals↗