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Biomedical subjects

G V Ianovskiĭ

Publications and source records attributed to G V Ianovskiĭ.

At least 19 recordsLinked to original sources
PubMed1998

[The hormone level of the blood from the aorta and the coronary sinus in patients with ischemic heart disease under conditions of preoperative stress].

A total of 156 patients with ischemic heart disease were examined under conditions of preoperative stress in a multiple-modality study performed with the aid of such techniques as echocardiography involving calculation of the myocardial mass index, coronaroventriculography, measurements of the adrenocorticotrophic hormone, hydrocortisone, somatotrophic hormone, triiodothyronine and thyroxin in the blood from the coronary sinus and aorta. A conclusion has been reached that emotional strain influences myocardial hypertrophy. A possible significance of the studied hormonal indices is shown together with features thereof in IHD patients presenting with different degrees of left ventricular hypertrophy.

Adult↗
PubMed1995

[Cardiodynamics and left ventricular myocardial contractile reserve in patients with dilated cardiomyopathy].

Cardiodynamics and contractile myocardial reserves were measured at radionuclide ventriculography and volume loading of the heart (upward position of the legs at 45 degrees) in 43 patients with dilated cardiomyopathy (DCM). The patients displayed a sharp fall in total and regional ejection fractions (BP), stroke volume (SV), cardiac index, a decrease in Vcf and maximum ejection rate (Vmax) in combination with notable cardiomegaly. There were two types of responses to loading test: positive (increased BP, SV, Vcf, Vmax, reduced end-systolic volume) and negative (decreased EP, SV, Vcf, Vmax, increased end-systolic volume) Inotropic effects evidencing the existence or depletion of myocardial contractile reserve. Loading test in DCM patients allows more objective evaluation of the patient's condition and validated therapeutic measures.

Adult↗
PubMed1993

[Left ventricular function in patients with dilated cardiomyopathy].

Functional state of left ventricle was studied in 43 patients with dilated cardiomyopathy. All the patients showed pronouncedly reduced total ejection, stroke volume and cardiac index, increased final diastolic and final systolic volumes, decreased ejection rate indices. Analysis of regional contractility of left ventricle allowed to detect significant fall of ejection fraction in 96.3% of segments. Diastolic dysfunction was characterized by disorders of isovolumetric relaxation, changes in hemodynamical structure and contribution of atrial systole to ventricular filling, decrease of volumetric compliance of left ventricle. The data obtained give a reason to consider that appropriate therapy of dilated cardiomyopathy should be carried out with taking into account both systolic and diastolic left ventricle dysfunction.

Adult↗
PubMed1993

[Cardiodynamics and myocardial contractile reserve in patients with hypertrophic cardiomyopathy].

Cardiodynamics and myocardial contractile reserve were studied in 60 patients with hypertrophic cardiomyopathy by using radionuclide ventriculography at rest and during graded exercise test. All findings that characterize cardiodynamics (normal or higher overall ejection fraction and stroke volume or lower end-systolic volume, higher maximum ejection rate) show the contractility of the left ventricle in patients with hypertrophic cardiomyopathy which can be regarded to be more severe. During graded exercise test, in patients with hypertrophic cardiomyopathy three types of reactions were identified: (1) positive inotropic effect; (2) negative inotropic effect; (3) intermediate (deviation of major cardiodynamic parameters was no more than 20-25% of the baseline levels). Identification of the above types allows one to assess the presence and conditions of myocardial contractile reserve implementation in these patients and to objectivize the choice of corrective drugs.

Adolescent↗
PubMed1992

[Late ventricular potentials and left ventricular performance in patients with hypertrophic cardiomyopathy].

Twenty patients with hypertrophic cardiomyopathy were examined. They were found to have late ventricular potentials in the disease, which were characterized by an increase in average QRS complex duration, a decrease in voltage, and a rise in the duration of last 40 msec of the QRS complex filtered. Such patients generally exhibited lower exercise tolerance in severe asymmetric left ventricular hypertrophy, which caused a significant deterioration of cardiac pump function.

Adolescent↗
PubMed1991

[Left ventricular hypertrophy as an indication for the prescribing of calcium antagonists in patients with ischemic heart disease].

An analysis of the dynamics of diastolic rigidity, contractile function of the left ventricle and physical load tolerance under the effect of single intakes of phynoptin and corinfar and their course use in patients with IHD showed that they were more effective in case of increased mass of the myocardium. This indicates that increased mass of the myocardium is an additional indication to calcium antagonists in these patients.

Adult↗
PubMed1991

[Comparative evaluation of oxygen supply during exercise in healthy persons in relation to smoking].

Seventy males aged 30-59 years who had no signs of coronary heart disease, as evidenced by the epidemiological criteria, and other risk factors were examined. The oxygen supply during exercise was comparatively assessed in relation to smoking. It was found that there were no significant differences in physical fitness parameters in terms of the volume of performed work, in the power of threshold exercise, and respective heart rate in smokers and non-smokers. However, the smokers displayed a double increase in oxygen debt, a substantial elevation of oxygen consumption per unit work at maximum exercise levels, prolongation of its recovery, a decrease in metabolic units, and a more substantial elevation of systolic and diastolic blood pressures. The oxygen and differential pulses were found to be significantly lower in smokers than in non-smokers.

Adult↗
PubMed1990

[Electrocardiographic indices in the assessment of left ventricular hypertrophy].

The authors compared the electrical activity of the heart with results of echocardiography during rest and during bicycle ergometry [correction of veloergometry] in 240 patients with ischemic heart disease, 60 patients with hypertensive disease and in 16 healthy persons. In some of the patients coronarography was carried out. It was established that the informative value of electrocardiography in assessment of the anatomo-functional state of the left ventricle depended on the contingent of the examined patients and reduces as disorders of the functional state of the myocardium tended to advance. The specificity and sensitivity of the electrocardiographic signs of left ventricular hypertrophy reduced in disturbances of ventricular conduction, presence of myocardial infarction in the anamnesis, increase of involvement of the cardiac arteries.

Adult↗
PubMed1990

[The functional assessment of left ventricular hypertrophy in patients with ischemic heart disease].

It was established that left ventricular hypertrophy in patients with ischemic heart disease associated with hypertensive disease reflects a functionally more intact myocardium than similar hypertrophy in analogous patients without hypertensive disease. Hypertrophy of the left ventricle in patients with ischemic heart of different severity may be considered an index of myocardial lesion and this should be considered in the treatment tactics.

Adult↗
PubMed1990

[Causes and significance of myocardial ischemia occurring during coronary-ventriculography in patients with ischemic heart disease].

A relationship was examined between the development of myocardial ischemia in patients with coronary heart disease before coronary ventriculography and the status of coronary vessels, coronary reserve, myocardial contractility, and the autonomic nervous system. Before coronary ventriculography, myocardial ischemia was found to occur in the patients when there was a marked activation in the sympathetic portion of the autonomic nervous system and a clear-cut decrease in coronary reserve. The occurrence of myocardial ischemia in the patients before coronary ventriculography contributed to decreased left ventricular myocardial contractility and increased the cardiodepressive effects of a contrast agent.

Adult↗
PubMed1990

[Electrocardiographic signs of hypertrophy of the interventricular septum in patients with hypertrophic cardiomyopathy].

An analysis of electrocardiographic signs of interventricular septum hypertrophy depending on the prevailing location as evidenced by echocardiographic data in 34 patients with hypertrophic cardiomyopathy established that local hypertrophy is reflected in changes of the depolarization phase as well as repolarization phase of the electrocardiogram of various degrees. It is concluded that the revealed changes should be considered, in particular, in dynamic observations, for their differentiation with possible analogous changes of the bioelectric activity of the myocardium in patients with ischemic heart disease.

Adult↗