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Biomedical subjects

G V Marie

Publications and source records attributed to G V Marie.

7 recordsLinked to original sources

Psychophysiological mechanisms of chronic headaches: investigation using pain induction and pain reduction procedures.

Psychophysiological investigations of tension headaches and migraines have produced inconsistent and inconclusive findings. The study reported here aimed to further explore headache mechanisms by repeating earlier research with two main variations. The first pertained to recording and analytic procedures: a different approach was taken to measuring and interpreting cephalic vascular activity. The second was in the experimental conditions used: pain levels were manipulated so that the psychophysiology of headaches could be studied under conditions of pain increasing and decreasing. The findings provided no support for the role of muscle tension as a headache mechanism. Tentative support was obtained for vascular models of headaches. Headaches were associated with distension of the superficial temporal artery between pressure pulses. The data suggested that local vasomotor activity might play a role in dilating the temporal artery but that the effect seemed driven by elevated blood pressure and heart rate.

Adult↗

Relaxation and stress management in the treatment of essential hypertension.

Thirty-two male and female hypertensives, 34 to 65 yr of age, systolic blood pressure (SBP) less than 200 mmHg and diastolic blood pressure (DBP) between 90 and 109 mmHg, were randomly allocated to receive either relaxation and stress management (experimental condition) or mild physical exercise (control condition). Half the participants were taking antihypertensive drugs, which were constant for six months prior to the study and controlled during the study. Outcome measures included various measures of blood pressure in the clinic and at home, cardiovascular responsiveness, moods and 24-hr urinary adrenaline and noradrenaline. The study schedule consisted of 3-months baseline, 10 weeks treatment and 3-months follow-up. Relaxation was superior to the control procedure in reducing blood pressure as assessed by nurses blind to the participants' treatment at post-treatment for DBP and at follow-up for DBP and SBP.

Adult↗

Self-control of interbeat interval and pulse transit time at rest and during exercise. A preliminary report.

Attempts were made to establish self-control of interbeat interval (IBI) and pulse transit time (PTT) by providing appropriate biofeedback information to volunteers at rest and during dynamic and isometric exercise. Product feedback (IBI X PTT) was found more reliable than simple heart rate (HR) and systolic blood pressure (SBP) during dynamic exercise. It also produced greater increases in IBI and PTT than did habituation or relaxation under the same conditions. Product feedback was also superior to the use of other techniques at rest, but PTT feedback did not produce significant control of pressor responses during isometric exercise. Possible reasons for this failure are discussed. Preliminary results of feedback training given to 7 anginal patients suggest that such procedures might help to lower nitroglycerin consumption, decrease the frequency of anginal attacks and increase exercise tolerance.

Angina Pectoris↗