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Biomedical subjects

G V Nikolaev

Publications and source records attributed to G V Nikolaev.

15 recordsLinked to original sources
PubMed2003

[The surgical lung volume reduction in patients with diffuse emphysema].

Twelve patients with severe chronic pulmonary obstructive disease complicated by a strong respiratory failure underwent lung volume reduction operations. An examination of the baseline functional parameters showed a significant outflow obstruction and lung hyperinflation. All the patients selected for the operation had a heterogeneous pattern of emphysema. Air leak from the lung suture was the main problem in the postoperative period. Long-term results were studied in 9 patients. A significant reduction of the respiratory failure and improvement of quality of life of the patients were noted. Significantly increased vital capacity, forced expiratory volume for 1 second, decreased residual volume and bronchial resistance were demonstrated.

Aged↗
PubMed1990

[Nervous and mental disorders in patients with chronic alcoholic pancreatitis].

Presented are the results of comprehensive CNS examinations in 53 alcoholics with chronic pancreatitis. Related psychopathological and neurological syndromes are specified. Hepatopancreatoduodenal and CNS abnormalities were found directly correlated. The addition of pancreatitis to alcoholism leads to development of encephalomyelopolyradiculoneurotic syndrome.

Adult↗
PubMed1984

[Neuropsychiatric disorders and bodily reactivity in thermal lesions].

The urgent questions of neuropsychic disorders related to thermal lesions are discussed on the basis of an analysis of the literature data and the results of the authors' long-term studies. It is shown that all these disturbances are formed in patients with deep burns affecting over 15% of the body's surface in the presence of marked disturbances of all links of the systemic anti-infection defence, the latter being conducive to the generalization of the infectious process. Thus, these pronounced disorders of the immunologic mechanisms of homeostasis are responsible for the background against which those severely burned develop the organic neuropsychopathological syndrome, burn-associated encephalopathy, which persists for a long time after the trauma.

B-Lymphocytes↗
PubMed1980

[Asthenic disorders in burn disease].

A total of 73 patients with burn disease were examined. The whole period of the disease was marked by a distinct asthenic symptomatology shown by predominance of physical asthenia, by stable and stereotypic mental disturbances. The asthenic disorders correlated with the somatic state of the patient. Such disorders were seen for a long period of time, and even after recovery. Apart from asthenic symptomatology, all the patients demonstrated disturbances in the intellectual sphere, and in intellectual-mnestic processes, which were also seen in the late periods of burn disease. The changes in the neurologic state were characterized by lesions of the cranial nerves, anizoreflexia of the hemitype, pathological reflexes in the hand and feet, vegetative-trophic disturbances indicating that all the patients who had extensive and deep burns developed encephalopathy.

Asthenia↗
PubMed1980

[Psychopathologic disorders in burns].

Psychopathological disturbances in 149 patients with burn disease are described during all stages of the disorder. Certain correlations with the period of burn disease, the depth and affected surface, somatic disturbances, premorbid personality traits, sex and age were demonstrated. Different variants of psychopathological disturbances and their traits in burn trauma in the acute period of burn disease are described. Variants of such disorders persisted in patients with burn encephalopathy in the late period of the disease from one to 20 years.

Acute Disease↗
PubMedDate not supplied

[Formation of conditioned reflexes to number of sequential stimuli in the dog].

The present experimental study deals with question, whether dogs are able to orient their behaviour to stimuli which differ only by the number of identical clicks presented in successive series with variable interstimulus interval. Some dogs elaborated alimentary or defensive motor conditioned reflexes nd differentiations to them being in classical conditions in experimental chamber. In other dogs running to the feeding trough was elaborated and a differentiation to it in response to series of clicks differing only by one signal. It was established that the parameters of conditioned positive and negative reactions (latency, rate and realization frequency) statistically depended on the number of clicks in the series and did not depend upon its temporal characteristics (interstimulus intervals and duration). The conclusion is made that in CNS of dogs, elementary form of counting a signals takes place, and that the integrated result of this count might serve as a key to evoke positive or negative conditioned reaction.

Adaptation, Psychological↗