PubMed Health⌕ Search

Biomedical subjects

G Viejo

Publications and source records attributed to G Viejo.

11 recordsLinked to original sources
PubMed1998

Serological markers of hepatitis A, B and C in first year student nurses.

OBJECTIVE: To know the prevalence of serological markers of hepatitis A, B and C virus in first year student nurses. SETTING: A transversal study of prevalence. SUBJECTS AND METHODS: 81 first year student nurses, mean age 20.6 years (18-37, S.D. 3.8), with demographic, epidemiologic and clinical variables, performing liver enzymes, anti-HAV IgG, anti-HBcore and anti-HCV. RESULTS: The anti-HAV IgG was positive in 9 students (11.1%), with a prevalence of 6.7% between 17 and 19 years (C.I.95% 1.7 to 19.3%), 8.7% between 20 and 22 years (C.I.95% 1.5 to 29.5%), 20% between 23 and 25 years (C.I.95% 10.5 to 70.1%), and 37.5% (C.I.95% 10.2 to 74.1) in those over 25 years (p < 0.001). No other significative variables existed according to age-group. Regarding hepatitis B virus, of the 65 not previously vaccinated, only 1 (1.5%, C.I.95% 0.08 to 9.4%) was immunized, and there were no cases of HBsAg positive. The anti-VHC was positive in one case (1.2%, C.I.95% 0.06 to 7.6%), RIBA indeterminate and with normal ALT. Only one student (1.2%) showed increased transaminase values, attributed to liver steatosis. None of the students had suffered any episode of acute clinic hepatitis. CONCLUSIONS: The anti-HAV IgG prevalence in first year student nurses in our area is very low, and it is not necessary to carry out prevacunal screening. The low prevalence of anti-Hbcore also rejects a similar screening with respect to HBV. There were no HBsAg or anti-HCV positive cases, but it should not be the cause of forgetting to take the universal precautions or giving a false sensation of security.

Biomarkers↗
PubMed1997

[Diagnosis of meningoencephalitis caused by herpes simplex virus type 1 using nested PCR in CSF samples].

BACKGROUND: The aim of this study was to achieve the early diagnosis of the neurologic alteration caused by the Herpes Simplex virus type 1 (HSV-1) with the nested PCR technique in CSF. PATIENTS AND METHODS: From January, 1994 to October, 1995, 140 CSF from 140 patients were studied in our laboratory. Ninety-five were diagnosed with viral meningoencephalitis (Group A) and 45 with other neurologic diseases (Group B). Nested PCR of HSV-1 and conventional viral cultures were carried out in all the cases. RESULTS: Laboratory diagnosis was achieved in 13 (13.68%) of Group A patients: in 12 (12.63%) HSV-1 genome was detected by nested PCR and in one patient adenovirus was isolated. In Group B, the HSV-1 was detected by nested PCR in 2 patients (4.44%). CONCLUSIONS: The results obtained demonstrate the usefulness of nested PCR in HSV-1 infection for the diagnosis of herpetic meningoencephalitis in initial stages of the disease, from a single CSF sample.

Herpes Simplex↗
PubMed1996

[The serum markers in the pregnant population of the basic health area of El Natahoyo (Gijón)].

OBJECTIVES: To find the prevalence of markers of rubeola, Toxoplasma, lues, HIV and hepatitis A, B and C viruses in the pregnant women of a health district; and these markers' correlations with epidemiological and socio-demographic antecedents. PATIENTS: 129 pregnant women from the 5.3 Health District in Asturias with birth predicted for between August 1994 and October 1995. A descriptive study of epidemiological, socio-demographic and serological data; statistical calculation with RSigma. RESULTS: 109 pregnant women (84.5%) were assessed, average age 28.6, including 9 abortions with path. analysis in the first three months. HIV was tested in 15 cases, all negative. Toxoplasma was positive in 46 cases, with no association with other variables. Rubeola was negative in 6 cases, all > 25 years old, with overall vaccination coverage of 42.2% and 64.7% for < 26-year-olds. One case of lues was found. The HC test was negative in all the pregnant women, with 4% of HBsAg+, related to being gypsy and to AF of hepatopathy. HA IgG was positive in 52 cases (52%) and more common among gypsies vs. the rest. In the latter group there was increasing prevalence according to age. CONCLUSIONS: 1) HIV screening is not common. 2) There is a high percentage of pregnant women with no immunity to Toxoplasma. 3) Low rubeola vaccination coverage among women under 26 was found. 4) There is a higher percentage of HBsAg+ cases in comparison with other areas, but not with the HC virus. 5) A high percentage of cases had no previous contact with the HA virus.

Adult↗
PubMed1992

Survey of Escherichia coli septicemia over a six-year period.

Escherichia coli was the most frequent species isolated from blood cultures in the Hospital Covadonga of Oviedo (Spain) over a six-year period (474 episodes, 15.3% of the total septicemias and 2.7 episodes per 1,000 patients). Escherichia coli strains were susceptible in greater than 95% of episodes to cefoxitin, cefotaxime, gentamicin, tobramycin and amikacin. In a series of 72 episodes, microbiological features and host factors were studied. No endemic stains were found. Type 1 fimbria was detected in 73.6% of strains and P-fimbriae in 12.5%, without correlation between P-fimbria and urinary infection; 84.7% of the strains were resistant to decomplement human serum; 61.1% produced aerobactin and 20.8% were hemolytic. Factors such as age, hospital location, metastatic focus and surgical treatment were significantly correlated with morbidity and mortality. The global mortality rate was 18%, and in 8.3% of cases was directly associated with septicemia.

Adult↗
PubMedDate not supplied

[The prevalence of hepatitis A, B and C viral markers in the population of Gijón between 26 and 65 years old].

The aim of this study was to know the prevalence of hepatitis A, B and C markers in an adult population in Gijón, Spain. A randomized, transversal sample according to the census was made in a population between 26 and 65 years of age in Gijón, analyzing demographic, epidemiologic and clinical variables, liver function tests, anti-HAV IgG, anti-HBcore and anti-HCV. Of the 476 individuals included a census error was detected in 26 (5.5%) and 340 (71.4%) were studied. Of these anti-HAV IgG was positive in 210 (61.8%) with prevalences of 17.9% from 26 to 30 years (CI: 95%, 11.1%-27.4%), 54.7% from 31 to 35 years (CI: 95%, 41.8%-67%), 73.6% from 36 to 40 years (CI: 95%, 59.4%-84.3%) and 93% (CI: 95%, 86.7%-96.5%) above 40 years of age (p < 0.001). No other significant variables were found adjusted by age groups. With regard to HBV, of the 331 unvaccinated cases, 35 (10.6, CI 95%, 7.6%-14.5%) presented immune markers and 4 (1.2% CI: 95%, 0.4%-3.3%) HBsAg positivity, with all having normal ALT and no viral replication. Anti-HCV was positive in 1.7% (CI: 95%, 0.7-3.9%), being significantly related to IVDA or tattoos. Hypertransaminasemias were detected in 18 (5.3%) being attributed to virus C (27.8%), alcoholism (27.8%) or obesity (44.4%). History of clinical manifestations of acute hepatitis was collected in 9.7% of the cases with no memory of the episode in 84.3% of the anti-HAV IgG positive cases, 79.5% of the anti-HBcore positive cases and 83.3% of the anti-HCV positive cases. The current curve of prevalence of anti-HAV IgG in the Gijón population varies in the decade from 30 to 40 years in age ranging from values discarding prevaccination screening under the age of 30 to levels of minimum susceptibility to infection above the age of 40. The low prevalence of anti-HBcore underestimates its use as prevaccination screening versus HBV in the population of Gijón. The prevalences of HBsAg or anti-HCV thereby make this area a zone of intermediate endemicity, with around 3% of the population being chronically infected by one of these viruses.

Adult↗