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Biomedical subjects

G Vincent

Publications and source records attributed to G Vincent.

At least 19 recordsLinked to original sources
PubMed1992

[Unsatisfactory results of intradiscal injection of triamcinolone hexacetonide in the treatment of sciatica caused by intervertebral disk herniation].

Sciatica caused by intervertebral disc herniation can be treated with intradiscal injection of chymopapain. A search for a cheaper and less allergizing product led to triamcinolone hexacetonide, this procedure being known as "nucleorthesis". The first results at 6 months were encouraging. In 3 centres where triamcinolone hexacetonide was tested with a more than 2 years' follow-up 92 patients could be evaluated. The results obtained were considered satisfactory in 34 patients (36.9 percent), but they were poor in 19 patients (20.6 percent), and 39 patients (42 percent) had to be operated upon within 2 years. Return to surgery took place within the 6 months following nucleorthesis in 18 patients (19.56 percent) and beyond this period in 17 patients (22.8 percent) with degradation of the results. Moreover, calcifications were found in 19 out of 38 patients; they were of varying size, sometimes detected only at computerized tomography, and some of them appeared to produce symptoms. All considered, the failure rates, the number of patients who required surgery and the occurrence of large and sometimes symptomatic calcifications make triamcinolone nucleorthesis unacceptable compared with the recognized percentages of success with papain nucleolysis and surgical operations. For these reasons, we consider that this treatment should be abandoned.

Anti-Inflammatory Agents↗
PubMed1992

[Weismann-Netter and Stuhl toxopachyosteosis. Apropos of 30 cases].

Toxopachyosteosis, a rare bone disease, was described in 1954 by Weissmann-Netter and Stuhl. This congenital osteopathy, which may be familial, is defined by an anteroposterior curvature (toxon = arc) and thickening (pachus = thick) of the shafts of both leg bones. Other bones may be affected. Short stature and delayed walking are other important special features of the disease. It is most often diagnosed late and by chance because of the minimal functional consequences of the deformities. Sequelae of vitamin D-deficient rickets are the main differential diagnosis. The aim of this study undertaken by the Bone and Calcium/Phosphorus Metabolism Section of the Société Française de Rhumatologie (French Society of Rheumatology) was an overall assessment of the disease. The authors report 30 cases of toxopachyosteosis and evaluate their main characteristics on the basis of data from the literature.

Adult↗
PubMed1992

[A case of Weismann-Netter and Stuhl toxopachyosteosis with new bone sites].

A case of Weismann-Netter-Stuhl toxopachyosteosis in a 63-year-old man is reported. Bone deformities had been present since the age of 18 months. Tibio-fibular dysmorphism was severe. Radiological evaluation revealed other lesions encountered more rarely: bilateral femoral incurvature and exostoses, bilateral coxa vara, radio-ulnar incurvature and flattening of the last ribs. Two other previously undescribed lesions were seen in this patient; bradymetacarpism of the last four rays of the left hand and dysmorphic lengthening of the left patella. This case illustrates the widespread nature and unusual extent of bone lesions in the context of toxopachyosteosis.

Bone Diseases, Developmental↗
PubMed1992

[Problems and eradication of Ambrosia artemisiifolia L. in Quebec in the urban and suburban environments].

Ambrosia artemisiifolia is a common weed in Canada and it is one of the most important source of aero-allergenic pollen in the north-eastern part of North America. It is a problem mostly along roads in urban or suburban areas. It is easily controlled by herbicides but their use is increasingly restricted because of environmental considerations. Therefore, new methods must be developed to control this weed. Three types of controls were evaluated against Ambrosia artemisiifolia along an expressway in the summer of 1990. The control methods were hand weeding, mowing at 2 cm, 5 cm, or 8 cm, and crushing by a roadroller. These treatments were done at different dates in the course of the summer. Hand weeding was the most effective in reducing pollen and seed production although it was also the most expensive. Mowing was very effective when it was done at a height of 2 cm from the soil. It is the only height at which seed production was significantly reduced. Mowing efficacy in reducing pollen production tended to decrease with the raising of the mowing blade. The efficiency of weed pulling or moving improved when they were performed later in the growing season. Crushing was not an effective method of control. Mowing or hand weeding cannot eradicate Ambrosia artemisiifolia but if they are consistently used, they could reduce its population level over several years by decreasing seed production. The treatments either eliminated pollen production or reduced it at least by 88%, thereby insuring a relative relief for people allergic to the pollen of this plant.

Agriculture↗
PubMed1991

[Effects on the bone metabolism of long-term treatment with antivitamins K1].

Oral anticoagulants (OC) prevent the activation by carboxylation of coagulation proteins. However this action also affects osteocalcin, or bone Gla-protein, a parameter of bone remodelling. Phosphorus and calcium metabolism, osteocalcin levels and bone mineral content were studied in twelve men aged under 60, and who had been taking OC for more than a year, in comparison with a paired group of nine controls with the same cardiovascular pathology but not taking anticoagulants. Osteocalcin levels were lower in the OC group (3.44 ng/ml) than in the control group (5.88 ng/ml) (p = 0.01). There was no significant difference in other phosphorus/calcium balance parameters nor in bone density between the two groups. No evidence was found of any osteopathy in the OC group, but the decrease in serum osteocalcin could result either from inhibition of its secretion or of its carboxylation, or from an action on the osteoblast.

Anticoagulants↗
PubMed1991

Late arterial erosion of a Crutchfield vascular clamp presenting with transient ischemic attacks: review of treatment options.

Crutchfield clamps were once widely used for proximal carotid artery ligation in the treatment of intracranial aneurysms and cavernous sinus fistulae. Consequently, there are a number of patients being followed who were treated with this device 10 to 15 years ago. The most important complication of this treatment modality in both the early and late postoperative period is thromboembolic phenomenon presenting as transient ischemic attacks, or a frank stroke. Because of the residual patient population with this device still in place, interval reports regarding the occurrence and treatment of late complications are important. We report a patient who underwent Crutchfield clamp application for control of a cavernous sinus fistula and had done well for 20 years when he developed transient ischemic attacks (TIA). Arteriography revealed a severe stenotic lesion (greater than 90%) in the common carotid artery with a patent internal carotid artery and no evidence of the previous fistula and an ulcerated plaque. At surgery, the pressure plate of the clamp had achieved an intraluminal position. The stenotic area was resected and an end to end anastomosis performed with complete resolution of symptoms after 18 months of follow-up. In this report we review the literature for complications of this device and discuss treatment options.

Arteriovenous Fistula↗
PubMed1990

[Surgery of severe ischemias and infections of the foot in the diabetic. (Role of arterial revascularization)].

From overall data on 54 diabetic patients, who, over a period of 7 years, underwent operations to save their feet from ischaemia (whether linked or not to infection), the authors study 31 cases of revascularization through arterial bridging in the diabetic's lower limbs. The lesions were identified by doppler examination followed by arteriography. Various types of bridging were undertaken: 24 femoro-popliteal bridges, including 16 super-articular and 8 sub-articular ones; and 7 femoro-distal bridges on the leg artery trunks. For the post operational period, only one amputation, resulting from precocious thrombosis in the graft, had been noted. All the patients had been followed up, and the authors remarked that, after an average lapse of 43 months, actuarial survival without amputation of the lower limb amounted to 94.97% after 7 years, and the level of actuarial permeability of the bridges amounted to 72.61% after the same period. The authors stress that revascularization indications should be the same for atheromatous diabetics as for non diabetics.

Aged↗
PubMed1989

[Spondylodiscitis disclosing bacterial endocarditis. Apropos of a case. Review of the literature].

The authors report a case of infectious spondylodiscitis revealing a staphylococcal endocarditis in a patient with a Carpentier aortic heterograft. This case, along with 60 descriptions from the literature, has enabled them to specify the characteristics of occurrence of endocarditis during a spondylodiscitis. The clinical factors in favor of this association are: a pre-existing cardiopathy, an oral port of entry, occurrence of other rheumatoid manifestations, even more the presence of complications of endocarditis. The laboratory factors in favor of an association are: discovery of an inflammatory anemia, of circulating immune complexes, of a cryoglobulinemia, of a rheumatoid factor, of hematuria. But it is mostly the demonstration of streptococcus in blood cultures and other samples that should be an indication to search for an endocarditis, the course of which dominates the prognosis.

Discitis↗