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Biomedical subjects

G W Bird

Publications and source records attributed to G W Bird.

At least 19 recordsLinked to original sources
PubMed1979

Anti-Cad lectin from the seeds of Leonurus cardiaca.

A predominantly Cad-specific lectin is present in the seeds of Leonurus cardiaca. Extracts of these seeds makes a valuable addition to reagents used in the elucidation of red cell polyagglutinability.

Antigens, Surface↗
PubMed1979

Sibship asymmetries of rhesus blood groups in the presence of maternal antibodies.

The genotypes of the children of R1r, R2r, and R1R2 fathers, and Rh-immunized rr mothers, were examined. R1r fathers had an excess of R1r over rr children, and R1R2 fathers had an excess of R1 r over R2r children. These asymmetries confirm the findings of a previous study. The possibilities of artefactual self-selection, of genotyping errors, and of errors in assigning paternity, were examined and excluded. Alternative models of genetic transmission and of antigenic structure were studied, but no basis for explaining the findings was found or formulated. Three possible biological explanations were formulated including (a) asymmetric segregation of the rhesus genes, (b) selective early fetal loss, and (c) a selective effect upon the performance of sperms bearing different haplotypes. The first of these three appeared unlikely. The data did not provide a basis for supporting or rejecting or differentiating the other two.

ABO Blood-Group System↗
PubMed1978

Tk polyagglutination associated with reduced A and H activity.

Tk polyagglutinable erythrocytes are described in which A and H activities were reduced. It is suggested that Bacteroides fragilis isolated from cultures of the patient's blood was responsible for each of these membrane modifications.

ABO Blood-Group System↗
PubMed1978

Inherited 'mosaicism' within the ABO blood group system.

A family with examples of the rare condition known as 'inherited mosaicism affecting the ABO blood groups' has been studied. In this family there were five examples of Bmos:O mosaicism. Blood group gene-specified transferase estimations were studied in this condition for the first time. In 'affected' members, levels of B gene-specified transferase were low, and amounted to only 7--10% of the activity of a normal control. It is proposed that Bmos is correctly classified as a new form of weak B.

ABO Blood-Group System↗